{"created":"2023-06-20T15:50:46.600519+00:00","id":3706,"links":{},"metadata":{"_buckets":{"deposit":"b1e55806-4a47-4648-b3ea-8f6f887c9c80"},"_deposit":{"created_by":29,"id":"3706","owners":[29],"pid":{"revision_id":0,"type":"depid","value":"3706"},"status":"published"},"_oai":{"id":"oai:redcross.repo.nii.ac.jp:00003706","sets":["95:28:69"]},"author_link":["8880","8881","8882"],"item_10002_biblio_info_7":{"attribute_name":"書誌情報","attribute_value_mlt":[{"bibliographicIssueDates":{"bibliographicIssueDate":"2011-02-01","bibliographicIssueDateType":"Issued"},"bibliographicIssueNumber":"1","bibliographicPageEnd":"19","bibliographicPageStart":"13","bibliographicVolumeNumber":"30","bibliographic_titles":[{"bibliographic_title":"静岡赤十字病院研究報"},{"bibliographic_title":"Journal of Japanese Red Cross Shizuoka Hospital","bibliographic_titleLang":"en"}]}]},"item_10002_description_5":{"attribute_name":"抄録","attribute_value_mlt":[{"subitem_description":"幼若血小板比率（immature platelet fraction:IPF）は多項目自動血球分析装置XE-2100で測定され，網血小板を反映すると考えられている．今回，IPFと染色体異常との関連について検討した．対象は，骨髄穿刺を行った333例の444検体を用いた．染色体異常は92検体（20.7％） に認められ，染色体異常を認める検体のIPFは7.6±6.9％，染色体異常を認めない検体の4.9±5.7％に比し有意に高値であった（p＜0.001）．染色体異常の出現率は，IPF5％未満15.5％，5～10％未満22.0％， 10％以上45.2％と増加した．特に，IPF10％以上の骨髄異形成症候群， 骨髄増殖性疾患，悪性リンパ腫では，高率に染色体異常が認められた．さらに，構造異常と数的異常を認める検体のIPFは， 10.0±8.4％と高値であった．以上の所見より，IPF 10％以上の検体では高率に染色体異常が認められ，染色体常を捉えるマーカーとしてIPFが有用である可能性が示唆された．","subitem_description_type":"Abstract"}]},"item_10002_publisher_8":{"attribute_name":"出版者","attribute_value_mlt":[{"subitem_publisher":"静岡赤十字病院"}]},"item_10002_source_id_11":{"attribute_name":"書誌レコードID","attribute_value_mlt":[{}]},"item_10002_source_id_9":{"attribute_name":"ISSN","attribute_value_mlt":[{"subitem_source_identifier":"0911-9833","subitem_source_identifier_type":"ISSN"}]},"item_10002_version_type_20":{"attribute_name":"著者版フラグ","attribute_value_mlt":[{"subitem_version_resource":"http://purl.org/coar/version/c_970fb48d4fbd8a85","subitem_version_type":"VoR"}]},"item_creator":{"attribute_name":"著者","attribute_type":"creator","attribute_value_mlt":[{"creatorNames":[{"creatorName":"黒山, 祥文"}],"nameIdentifiers":[{},{}]},{"creatorNames":[{"creatorName":"大棟, 久美江"}],"nameIdentifiers":[{},{}]},{"creatorNames":[{"creatorName":"川口, 貴子"}],"nameIdentifiers":[{},{}]}]},"item_files":{"attribute_name":"ファイル情報","attribute_type":"file","attribute_value_mlt":[{"accessrole":"open_date","date":[{"dateType":"Available","dateValue":"2013-07-01"}],"displaytype":"simple","filename":"jrcsh3001_13-19.pdf","filesize":[{"value":"548.8 kB"}],"format":"application/pdf","licensetype":"license_note","mimetype":"application/pdf","url":{"label":"pdf002517","url":"https://redcross.repo.nii.ac.jp/record/3706/files/jrcsh3001_13-19.pdf"},"version_id":"e76c5d5f-41c2-4549-8e9c-be8e8e1ab7d3"}]},"item_keyword":{"attribute_name":"キーワード","attribute_value_mlt":[{"subitem_subject":"幼若血小板比率 （IPF）","subitem_subject_scheme":"Other"},{"subitem_subject":"染色体検査","subitem_subject_scheme":"Other"},{"subitem_subject":"XE-2100","subitem_subject_scheme":"Other"},{"subitem_subject":"染色体異常","subitem_subject_scheme":"Other"},{"subitem_subject":"造血器腫瘍","subitem_subject_scheme":"Other"},{"subitem_subject":"Immature platelet fraction (IPF)","subitem_subject_language":"en","subitem_subject_scheme":"Other"},{"subitem_subject":"chromosome","subitem_subject_language":"en","subitem_subject_scheme":"Other"},{"subitem_subject":"XE-2100","subitem_subject_language":"en","subitem_subject_scheme":"Other"},{"subitem_subject":"abnormality","subitem_subject_language":"en","subitem_subject_scheme":"Other"},{"subitem_subject":"hematological disorder","subitem_subject_language":"en","subitem_subject_scheme":"Other"}]},"item_language":{"attribute_name":"言語","attribute_value_mlt":[{"subitem_language":"jpn"}]},"item_resource_type":{"attribute_name":"資源タイプ","attribute_value_mlt":[{"resourcetype":"departmental bulletin paper","resourceuri":"http://purl.org/coar/resource_type/c_6501"}]},"item_title":"幼若血小板比率と染色体異常の関連性について－特に， 血液疾患を中心に－","item_titles":{"attribute_name":"タイトル","attribute_value_mlt":[{"subitem_title":"幼若血小板比率と染色体異常の関連性について－特に， 血液疾患を中心に－"},{"subitem_title":"Regarding the relation between IPF (immature platelet fraction) and chromosomal abnormality, mainly hematological disorder","subitem_title_language":"en"}]},"item_type_id":"10002","owner":"29","path":["69"],"pubdate":{"attribute_name":"公開日","attribute_value":"2013-07-01"},"publish_date":"2013-07-01","publish_status":"0","recid":"3706","relation_version_is_last":true,"title":["幼若血小板比率と染色体異常の関連性について－特に， 血液疾患を中心に－"],"weko_creator_id":"29","weko_shared_id":-1},"updated":"2023-06-20T22:08:44.856087+00:00"}