{"created":"2023-06-20T15:50:44.554921+00:00","id":3656,"links":{},"metadata":{"_buckets":{"deposit":"3a8875c7-49fa-42c3-a8b8-46689456f1f0"},"_deposit":{"created_by":29,"id":"3656","owners":[29],"pid":{"revision_id":0,"type":"depid","value":"3656"},"status":"published"},"_oai":{"id":"oai:redcross.repo.nii.ac.jp:00003656","sets":["99:64:166"]},"author_link":["8489","8404","380","49","8715","8716","214","129","192"],"item_5_biblio_info_7":{"attribute_name":"書誌情報","attribute_value_mlt":[{"bibliographicIssueDates":{"bibliographicIssueDate":"1996-03-01","bibliographicIssueDateType":"Issued"},"bibliographicIssueNumber":"1","bibliographicPageEnd":"30","bibliographicPageStart":"24","bibliographicVolumeNumber":"1","bibliographic_titles":[{"bibliographic_title":"小松島赤十字病院医学雑誌"},{"bibliographic_title":"Komatushima Red Cross Hospital Medical Journal","bibliographic_titleLang":"en"}]}]},"item_5_description_5":{"attribute_name":"抄録","attribute_value_mlt":[{"subitem_description":"平成4年1月から、5年10月の聞に、当科でIFN治療を行った慢性肝炎C型患者は109例であるが、今回、IFN (r-α2a9MU、n-α 6MU)3週連投、後に週3回、計6ヶ月のスケジュールで治療した症例95例のうち、中止、転医、脱落例などをのぞく63例で治療スケジュールを完遂できた。この63例と中止例10例について治療成績を検討した。IFN終了後、1年以上、GOT、GPT、r-GTPの正常化持続例(A群)は25例(39.7％)、正常化後再燃(B群)20例(31.7％)、非正常化(C群)18例(28.6％)で、うち無反応(D群)6例(9.5％)であった。各群間で、年齢、性、r-GTP、血小板数、ADA、HAIscore、IFNの種類別につき、また、A、B群間では正常化までのIFN投与期間についても、統計的に差を検討した。A.C、A.D、B.C、B.D間でr-GTPに有意差がみられた(p<0.001)。A.B 聞で血小板数(p<0.01)、A.C問でHAIscore(P <O.05)にも有意差を認めた。r-GTPはIFN療法の予後予測因子の1つとして加え得る可能性がある。今後さらに治療効果を上げるためには、IFNと他剤の併用療法を検討する必要があろう。","subitem_description_type":"Abstract"}]},"item_5_full_name_3":{"attribute_name":"著者別名","attribute_value_mlt":[{"nameIdentifiers":[{"nameIdentifierScheme":"WEKO"}],"names":[{"name":"NAGATA, Junichi"}]}]},"item_5_heading_23":{"attribute_name":"見出し","attribute_value_mlt":[{"subitem_heading_banner_headline":"原著","subitem_heading_language":"ja"}]},"item_5_publisher_8":{"attribute_name":"出版者","attribute_value_mlt":[{"subitem_publisher":"小松島赤十字病院"}]},"item_5_source_id_9":{"attribute_name":"ISSN","attribute_value_mlt":[{"subitem_source_identifier":"1341-8262","subitem_source_identifier_type":"ISSN"}]},"item_5_version_type_20":{"attribute_name":"著者版フラグ","attribute_value_mlt":[{"subitem_version_resource":"http://purl.org/coar/version/c_970fb48d4fbd8a85","subitem_version_type":"VoR"}]},"item_creator":{"attribute_name":"著者","attribute_type":"creator","attribute_value_mlt":[{"creatorNames":[{"creatorName":"長田, 淳一"}],"nameIdentifiers":[{},{}]},{"creatorNames":[{"creatorName":"佐藤, 幸一"}],"nameIdentifiers":[{},{}]},{"creatorNames":[{"creatorName":"宮, 恵子"}],"nameIdentifiers":[{},{}]},{"creatorNames":[{"creatorName":"猪本, 享司"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"木村, 聡"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"川井, 恵子"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"岡, 耕一"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"藤井, 義幸"}],"nameIdentifiers":[{},{}]}]},"item_files":{"attribute_name":"ファイル情報","attribute_type":"file","attribute_value_mlt":[{"accessrole":"open_date","date":[{"dateType":"Available","dateValue":"2013-05-21"}],"displaytype":"simple","filename":"trchmj601_24-30.pdf","filesize":[{"value":"3.0 MB"}],"format":"application/pdf","licensetype":"license_note","mimetype":"application/pdf","url":{"label":"pdf002452","url":"https://redcross.repo.nii.ac.jp/record/3656/files/trchmj601_24-30.pdf"},"version_id":"e3bb085a-8907-41b4-b7ad-677fa1455575"}]},"item_keyword":{"attribute_name":"キーワード","attribute_value_mlt":[{"subitem_subject":"C型肝炎","subitem_subject_scheme":"Other"},{"subitem_subject":"IFN治療","subitem_subject_scheme":"Other"},{"subitem_subject":"r-GTP","subitem_subject_scheme":"Other"},{"subitem_subject":"シメチジン","subitem_subject_scheme":"Other"}]},"item_language":{"attribute_name":"言語","attribute_value_mlt":[{"subitem_language":"jpn"}]},"item_resource_type":{"attribute_name":"資源タイプ","attribute_value_mlt":[{"resourcetype":"technical report"}]},"item_title":"慢性肝炎C型のＩＦＮ治療","item_titles":{"attribute_name":"タイトル","attribute_value_mlt":[{"subitem_title":"慢性肝炎C型のＩＦＮ治療"},{"subitem_title":"IFN-therapy of Chronic hepatitis type C","subitem_title_language":"en"}]},"item_type_id":"5","owner":"29","path":["166"],"pubdate":{"attribute_name":"公開日","attribute_value":"2013-05-21"},"publish_date":"2013-05-21","publish_status":"0","recid":"3656","relation_version_is_last":true,"title":["慢性肝炎C型のＩＦＮ治療"],"weko_creator_id":"29","weko_shared_id":29},"updated":"2023-06-20T19:11:12.252407+00:00"}