{"created":"2023-06-20T15:50:38.778000+00:00","id":3510,"links":{},"metadata":{"_buckets":{"deposit":"cfe4336f-18bf-4d67-8048-0e05e109a850"},"_deposit":{"created_by":18,"id":"3510","owners":[18],"pid":{"revision_id":0,"type":"depid","value":"3510"},"status":"published"},"_oai":{"id":"oai:redcross.repo.nii.ac.jp:00003510","sets":["99:64:163"]},"author_link":["207","8405","8404","49","380","8320","129"],"item_10002_biblio_info_7":{"attribute_name":"書誌情報","attribute_value_mlt":[{"bibliographicIssueDates":{"bibliographicIssueDate":"1999-03-01","bibliographicIssueDateType":"Issued"},"bibliographicIssueNumber":"1","bibliographicPageEnd":"5","bibliographicPageStart":"1","bibliographicVolumeNumber":"4","bibliographic_titles":[{"bibliographic_title":"小松島赤十字病院医学雑誌"},{"bibliographic_title":"Komatushima Red Cross I-Iospital Medical Journal","bibliographic_titleLang":"en"}]}]},"item_10002_description_5":{"attribute_name":"抄録","attribute_value_mlt":[{"subitem_description":"糖尿病を合併した63歳女性の自己免疫性肝炎(以下AIH)患者にウルソデオキシコール酸(以下UDCA)600mg/日の投与を行い臨床的、組織学的に改善した症例を経験したが、その後UDCAにて治療した3例のAIH症例を加え治療成績を報告する。年齢は58~64歳、女性3倒、男性1例であった。AIHスコアーによる診断では、全例とも確診例である。投与UD CA は600 ~900mg/ 日であり、短期、強力ネオミノファーゲンC (SNMC)を併用した。治療前GPTは各々338、412，108，118IU/Lであり、UDCA投与後GPTの正常化までの期間は1週間、3ヶ月、2ヶ月、6ヶ月であった。治療前の組織はいずれも肝実質と門脈域周囲の変化が主体で、I例以外、線維化は軽度であった。GPT正常化後の組織は実質と門脈周囲での改善が顕著であった。UDCAの治療効果は症例によりぱらつきが大きいが、ステロイドに比べ副作用の点で有利であり、初回治療に際し第一選択薬のーっとして考慮すべき薬剤と考えた。","subitem_description_type":"Abstract"}]},"item_10002_heading_23":{"attribute_name":"見出し","attribute_value_mlt":[{"subitem_heading_banner_headline":"原著","subitem_heading_language":"ja"}]},"item_10002_publisher_8":{"attribute_name":"出版者","attribute_value_mlt":[{"subitem_publisher":"小松島赤十字病院"}]},"item_10002_relation_17":{"attribute_name":"関連サイト","attribute_value_mlt":[{"subitem_relation_name":[{"subitem_relation_name_text":"徳島赤十字病院"}],"subitem_relation_type_id":{}}]},"item_10002_source_id_9":{"attribute_name":"ISSN","attribute_value_mlt":[{"subitem_source_identifier":"1341-8262","subitem_source_identifier_type":"ISSN"}]},"item_10002_version_type_20":{"attribute_name":"著者版フラグ","attribute_value_mlt":[{"subitem_version_resource":"http://purl.org/coar/version/c_970fb48d4fbd8a85","subitem_version_type":"VoR"}]},"item_creator":{"attribute_name":"著者","attribute_type":"creator","attribute_value_mlt":[{"creatorNames":[{"creatorName":"木村, 聡"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"長田, 淳一"}],"nameIdentifiers":[{},{}]},{"creatorNames":[{"creatorName":"宮, 恵子"}],"nameIdentifiers":[{},{}]},{"creatorNames":[{"creatorName":"佐藤, 幸一"}],"nameIdentifiers":[{},{}]},{"creatorNames":[{"creatorName":"原田, 真"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"市原, 寿江"}],"nameIdentifiers":[{},{}]}]},"item_files":{"attribute_name":"ファイル情報","attribute_type":"file","attribute_value_mlt":[{"accessrole":"open_date","date":[{"dateType":"Available","dateValue":"2013-05-14"}],"displaytype":"simple","filename":"trchmj401_1-5.pdf","filesize":[{"value":"2.4 MB"}],"format":"application/pdf","licensetype":"license_note","mimetype":"application/pdf","url":{"label":"pdf002320","url":"https://redcross.repo.nii.ac.jp/record/3510/files/trchmj401_1-5.pdf"},"version_id":"fdef8d2d-22d3-4468-bead-8add1feb6420"}]},"item_keyword":{"attribute_name":"キーワード","attribute_value_mlt":[{"subitem_subject":"AIH","subitem_subject_scheme":"Other"},{"subitem_subject":"UDCA","subitem_subject_scheme":"Other"},{"subitem_subject":"SNMC","subitem_subject_scheme":"Other"},{"subitem_subject":"ステロイド","subitem_subject_scheme":"Other"},{"subitem_subject":"AIH","subitem_subject_language":"en","subitem_subject_scheme":"Other"},{"subitem_subject":"UDCA","subitem_subject_language":"en","subitem_subject_scheme":"Other"},{"subitem_subject":"SNMC","subitem_subject_language":"en","subitem_subject_scheme":"Other"},{"subitem_subject":"steroids","subitem_subject_language":"en","subitem_subject_scheme":"Other"}]},"item_language":{"attribute_name":"言語","attribute_value_mlt":[{"subitem_language":"jpn"}]},"item_resource_type":{"attribute_name":"資源タイプ","attribute_value_mlt":[{"resourcetype":"departmental bulletin paper","resourceuri":"http://purl.org/coar/resource_type/c_6501"}]},"item_title":"自己免疫性肝炎におけるウルソデオキシコール酸（ＵＤＣＡ）の治療効果","item_titles":{"attribute_name":"タイトル","attribute_value_mlt":[{"subitem_title":"自己免疫性肝炎におけるウルソデオキシコール酸（ＵＤＣＡ）の治療効果"},{"subitem_title":"Therapeutic Effects of UDCA in Autoimmune Hepatitis","subitem_title_language":"en"}]},"item_type_id":"10002","owner":"18","path":["163"],"pubdate":{"attribute_name":"公開日","attribute_value":"2013-05-14"},"publish_date":"2013-05-14","publish_status":"0","recid":"3510","relation_version_is_last":true,"title":["自己免疫性肝炎におけるウルソデオキシコール酸（ＵＤＣＡ）の治療効果"],"weko_creator_id":"18","weko_shared_id":18},"updated":"2023-06-20T20:36:59.606595+00:00"}