{"created":"2023-06-20T15:50:37.774189+00:00","id":3485,"links":{},"metadata":{"_buckets":{"deposit":"a5a20c70-9bcf-452f-b929-5d44c617e9f8"},"_deposit":{"created_by":18,"id":"3485","owners":[18],"pid":{"revision_id":0,"type":"depid","value":"3485"},"status":"published"},"_oai":{"id":"oai:redcross.repo.nii.ac.jp:00003485","sets":["99:64:181"]},"author_link":["45","122","8345","48","44","292","6638","8344","8339","47"],"item_5_biblio_info_7":{"attribute_name":"書誌情報","attribute_value_mlt":[{"bibliographicIssueDates":{"bibliographicIssueDate":"2013-03-25","bibliographicIssueDateType":"Issued"},"bibliographicIssueNumber":"1","bibliographicPageEnd":"65","bibliographicPageStart":"61","bibliographicVolumeNumber":"18","bibliographic_titles":[{"bibliographic_title":"徳島赤十字病院医学雑誌"},{"bibliographic_title":"Tokushima Red Cross Hospital Medical Journal","bibliographic_titleLang":"en"}]}]},"item_5_description_5":{"attribute_name":"抄録","attribute_value_mlt":[{"subitem_description":"症例は68歳，女性．45歳頃からバセドウ病と診断され，治療が開始されたが，この頃から血小板数は少なく，Plt 3～８×104／μl 程度であった．62歳時に甲状腺亜全摘術の術前検査でPlt4.0×14／μl のため，骨髄検査などが施行され，特発性血小板性紫斑病（ITP）と診断された．60歳より糖尿病を指摘され，近医で食事療法と経口薬治療を開始し，一旦は改善していたが，徐々に血糖コントロールが悪化するため，当科に入院した．BMI 25.8kg／m2，Plt 7.6×104／μl，HbA１c（NGSP）8.9％で，空腹時血中CPR 1.0ng／ml，尿中CPR 38.4μg／日と内因性インスリン分泌は低下していた．\r\nGAD 抗体105.9U／ml，IA-２抗体21.5U／ml と膵島関連自己抗体が陽性であったことから，緩徐進行１型糖尿病と診断し，強化インスリン療法を導入した．また，PA-IgG23ng／107cell，TPO 抗体22.0IU／ml，抗核抗体80倍であり，HLA typing ではDR４を有していた．1型糖尿病と自己免疫性甲状腺疾患の合併は多腺性自己免疫症候群３型として知られているが，ITP の合併は稀であり，自己免疫機序に基づくこれらの病態を考える上で興味深い．","subitem_description_type":"Abstract"}]},"item_5_full_name_3":{"attribute_name":"著者別名","attribute_value_mlt":[{"nameIdentifiers":[{"nameIdentifierScheme":"WEKO"}],"names":[{"name":"NAITO, 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","subitem_source_identifier_type":"ISSN"}]},"item_5_version_type_20":{"attribute_name":"著者版フラグ","attribute_value_mlt":[{"subitem_version_resource":"http://purl.org/coar/version/c_970fb48d4fbd8a85","subitem_version_type":"VoR"}]},"item_creator":{"attribute_name":"著者","attribute_type":"creator","attribute_value_mlt":[{"creatorNames":[{"creatorName":"内藤, 伸仁"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"金崎, 淑子"}],"nameIdentifiers":[{},{}]},{"creatorNames":[{"creatorName":"上田, 紗代"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"井上, 広基"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"中内, 佳奈子"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"宮井, 優"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"村上, 尚嗣"}],"nameIdentifiers":[{},{}]},{"creatorNames":[{"creatorName":"島田, 直"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"新谷, 保実"}],"nameIdentifiers":[{},{}]}]},"item_files":{"attribute_name":"ファイル情報","attribute_type":"file","attribute_value_mlt":[{"accessrole":"open_date","date":[{"dateType":"Available","dateValue":"2013-05-11"}],"displaytype":"simple","filename":"trchmj1801_61-65.pdf","filesize":[{"value":"319.5 kB"}],"format":"application/pdf","licensetype":"license_note","mimetype":"application/pdf","url":{"label":"pdf002300","url":"https://redcross.repo.nii.ac.jp/record/3485/files/trchmj1801_61-65.pdf"},"version_id":"133b380d-6feb-4e66-83ee-95354d8bf2ae"}]},"item_keyword":{"attribute_name":"キーワード","attribute_value_mlt":[{"subitem_subject":"バセドウ病","subitem_subject_scheme":"Other"},{"subitem_subject":"特発性血小板減少性紫斑病","subitem_subject_scheme":"Other"},{"subitem_subject":"緩徐進行１型糖尿病","subitem_subject_scheme":"Other"},{"subitem_subject":"多腺性自己免疫症候群","subitem_subject_scheme":"Other"},{"subitem_subject":"Graves’ disease","subitem_subject_language":"en","subitem_subject_scheme":"Other"},{"subitem_subject":"idiopathic thrombocytopenic purpura（ITP）","subitem_subject_language":"en","subitem_subject_scheme":"Other"},{"subitem_subject":"slowly progressive insulin-dependent diabetes mellitus","subitem_subject_language":"en","subitem_subject_scheme":"Other"},{"subitem_subject":"polyglandular autoimmune syndrome","subitem_subject_language":"en","subitem_subject_scheme":"Other"}]},"item_language":{"attribute_name":"言語","attribute_value_mlt":[{"subitem_language":"jpn"}]},"item_resource_type":{"attribute_name":"資源タイプ","attribute_value_mlt":[{"resourcetype":"technical report"}]},"item_title":"バセドウ病に特発性血小板減少性紫斑病を合併し、その後、緩徐進行１型糖尿病を発症した多腺性自己免疫症候群３型の１例","item_titles":{"attribute_name":"タイトル","attribute_value_mlt":[{"subitem_title":"バセドウ病に特発性血小板減少性紫斑病を合併し、その後、緩徐進行１型糖尿病を発症した多腺性自己免疫症候群３型の１例"},{"subitem_title":"A Case of Autoimmune Polyglandular Syndrome Type ３ Complicated by Graves’ Disease and Idiopathic Thrombocytopenic PurpuraThat Developed Slowly Progressive Insulin-dependent Diabetes Mellitus","subitem_title_language":"en"}]},"item_type_id":"5","owner":"18","path":["181"],"pubdate":{"attribute_name":"公開日","attribute_value":"2013-05-11"},"publish_date":"2013-05-11","publish_status":"0","recid":"3485","relation_version_is_last":true,"title":["バセドウ病に特発性血小板減少性紫斑病を合併し、その後、緩徐進行１型糖尿病を発症した多腺性自己免疫症候群３型の１例"],"weko_creator_id":"18","weko_shared_id":18},"updated":"2023-06-20T22:05:16.473475+00:00"}