{"created":"2023-06-20T15:50:36.897341+00:00","id":3463,"links":{},"metadata":{"_buckets":{"deposit":"52f99b3d-cca1-4367-9d66-26297a7286ba"},"_deposit":{"created_by":18,"id":"3463","owners":[18],"pid":{"revision_id":0,"type":"depid","value":"3463"},"status":"published"},"_oai":{"id":"oai:redcross.repo.nii.ac.jp:00003463","sets":["99:64:160"]},"author_link":["93","92","8313","8312","8314"],"item_5_biblio_info_7":{"attribute_name":"書誌情報","attribute_value_mlt":[{"bibliographicIssueDates":{"bibliographicIssueDate":"2002-03-01","bibliographicIssueDateType":"Issued"},"bibliographicIssueNumber":"1","bibliographicPageEnd":"47","bibliographicPageStart":"43","bibliographicVolumeNumber":"7","bibliographic_titles":[{"bibliographic_title":"徳島赤十字病院医学雑誌"},{"bibliographic_title":"Tokushima Red Cross Hospital Medical Journal","bibliographic_titleLang":"en"}]}]},"item_5_description_5":{"attribute_name":"抄録","attribute_value_mlt":[{"subitem_description":"近年増加傾向にある中枢神経系悪性リンパ腫2症例に対し、メソトレキセート大量療法(HDMTX療法)を施行したので若干の文献的考察を加え報告する。症例lは67歳男性、左不全片麻坤で発症した。ステロイド療法後、計4回のHDMTX療法を施行した。経過中腫瘍再増大を認め、MTX投与時間、各クール聞の短縮、LV Oeukovolin)救援開始時間の延長等を行った。その後放射線療法、yナイフを施行した。症例2は73歳男性、左不全片麻揮にて発症した。ステロイド療法後HDMTX療法を3クール施行した。経過中MTX血中濃度が中毒域となり、また肝腎機能悪化あり、LV救援を頻回に早期より行い、hydrationを十分に行った。現在2症例はそれぞれ発症後18ヶ月、9ヶ月(平成13年12月現在)が経過しているが、腫揚の再増大等なく経過良好である。以上の経験より厳重な監視下で行えばHDMTX療法は比較的安全で有効な治療法と考えられた。","subitem_description_type":"Abstract"}]},"item_5_full_name_3":{"attribute_name":"著者別名","attribute_value_mlt":[{"nameIdentifiers":[{"nameIdentifierScheme":"WEKO"}],"names":[{"name":"NAKAISO, Mami"}]}]},"item_5_heading_23":{"attribute_name":"見出し","attribute_value_mlt":[{"subitem_heading_banner_headline":"症例","subitem_heading_language":"ja"}]},"item_5_publisher_8":{"attribute_name":"出版者","attribute_value_mlt":[{"subitem_publisher":"徳島赤十字病院"}]},"item_5_relation_17":{"attribute_name":"関連サイト","attribute_value_mlt":[{"subitem_relation_name":[{"subitem_relation_name_text":"徳島赤十字病院"}],"subitem_relation_type_id":{"subitem_relation_type_id_text":"http://www.tokushima-med.jrc.or.jp/hospital/medical/2002pdf/011.pdf","subitem_relation_type_select":"URI"}}]},"item_5_source_id_9":{"attribute_name":"ISSN","attribute_value_mlt":[{"subitem_source_identifier":"1346-9878","subitem_source_identifier_type":"ISSN"}]},"item_5_version_type_20":{"attribute_name":"著者版フラグ","attribute_value_mlt":[{"subitem_version_resource":"http://purl.org/coar/version/c_970fb48d4fbd8a85","subitem_version_type":"VoR"}]},"item_creator":{"attribute_name":"著者","attribute_type":"creator","attribute_value_mlt":[{"creatorNames":[{"creatorName":"中磯, 真実"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"岡, 博文"}],"nameIdentifiers":[{},{}]},{"creatorNames":[{"creatorName":"三宅, 一"}],"nameIdentifiers":[{},{}]},{"creatorNames":[{"creatorName":"依田, 啓司"}],"nameIdentifiers":[{}]}]},"item_files":{"attribute_name":"ファイル情報","attribute_type":"file","attribute_value_mlt":[{"accessrole":"open_date","date":[{"dateType":"Available","dateValue":"2013-05-11"}],"displaytype":"simple","filename":"trchmj701_43-47.pdf","filesize":[{"value":"2.4 MB"}],"format":"application/pdf","licensetype":"license_note","mimetype":"application/pdf","url":{"label":"pdf002229","url":"https://redcross.repo.nii.ac.jp/record/3463/files/trchmj701_43-47.pdf"},"version_id":"6591977c-a54e-41b5-a5ed-e4102006bf11"}]},"item_keyword":{"attribute_name":"キーワード","attribute_value_mlt":[{"subitem_subject":"CNS lynphoma","subitem_subject_scheme":"Other"},{"subitem_subject":"high-dose MTX therapy","subitem_subject_scheme":"Other"},{"subitem_subject":"Leukovolin（LV）rescue","subitem_subject_scheme":"Other"},{"subitem_subject":"CNS lymphoma","subitem_subject_language":"en","subitem_subject_scheme":"Other"},{"subitem_subject":"high-dose MTX therapy","subitem_subject_language":"en","subitem_subject_scheme":"Other"},{"subitem_subject":"leukovolin (L V) rescue","subitem_subject_language":"en","subitem_subject_scheme":"Other"}]},"item_language":{"attribute_name":"言語","attribute_value_mlt":[{"subitem_language":"jpn"}]},"item_resource_type":{"attribute_name":"資源タイプ","attribute_value_mlt":[{"resourcetype":"technical report"}]},"item_title":"メソトレキセート大量療法を施行した中枢神経系悪性リンパ腫の2症例","item_titles":{"attribute_name":"タイトル","attribute_value_mlt":[{"subitem_title":"メソトレキセート大量療法を施行した中枢神経系悪性リンパ腫の2症例"},{"subitem_title":"Two Patients with Malignant CNS Lymphoma for Whom High-dose I\\~ethotrexate Therapy was Given","subitem_title_language":"en"}]},"item_type_id":"5","owner":"18","path":["160"],"pubdate":{"attribute_name":"公開日","attribute_value":"2013-05-11"},"publish_date":"2013-05-11","publish_status":"0","recid":"3463","relation_version_is_last":true,"title":["メソトレキセート大量療法を施行した中枢神経系悪性リンパ腫の2症例"],"weko_creator_id":"18","weko_shared_id":18},"updated":"2023-06-20T22:04:50.705733+00:00"}