{"created":"2023-06-20T15:50:34.796577+00:00","id":3409,"links":{},"metadata":{"_buckets":{"deposit":"2df85e0a-0b84-4ebb-9f8c-022c4bdac9f0"},"_deposit":{"created_by":18,"id":"3409","owners":[18],"pid":{"revision_id":0,"type":"depid","value":"3409"},"status":"published"},"_oai":{"id":"oai:redcross.repo.nii.ac.jp:00003409","sets":["99:64:116"]},"author_link":["348","8097","8197","8098","6753","372","8196","6643","8198","8199","364"],"item_5_biblio_info_7":{"attribute_name":"書誌情報","attribute_value_mlt":[{"bibliographicIssueDates":{"bibliographicIssueDate":"2007-03-01","bibliographicIssueDateType":"Issued"},"bibliographicIssueNumber":"1","bibliographicPageEnd":"182","bibliographicPageStart":"178","bibliographicVolumeNumber":"12","bibliographic_titles":[{"bibliographic_title":"徳島赤十字病院医学雑誌"},{"bibliographic_title":"Tokushima Red Cross Hospital Medical Journal","bibliographic_titleLang":"en"}]}]},"item_5_description_5":{"attribute_name":"抄録","attribute_value_mlt":[{"subitem_description":"胸腹部大動脈瘤では,補助循環を用いずに大動脈単純遮断で手術を行うことがあり,その際には肝臓および腎臓への血流が一時的に遮断されるため,プロポフォールの血中濃度が大きく変化すると考えられる.今回我々は2症例で,大動脈単純遮断前後のプロポフォールの血漿中全濃度および非結合型濃度を測定し,予測血中濃度と比較検討したので報告する.麻酔導入後,プロポフォールは2mg/kg/hr の速度で持続投与した.大動脈単純遮断中にプロポフォールの血漿中全濃度および非結合型濃度が上昇し,血漿中全濃度は遮断前と比較しておよそ1.8倍に上昇した.遮断解除後には比較的速やかに低下し,遮断解除後30分から60分で遮断前の値に回復した.シミュレーションによる予測血中濃度と実測値の関連は,症例1では実測値がやや低めであったが,症例2ではよく一致しており,あらかじめプロポフォールの変化を予測することが可能と考えられた.","subitem_description_type":"Abstract"}]},"item_5_full_name_3":{"attribute_name":"著者別名","attribute_value_mlt":[{"nameIdentifiers":[{"nameIdentifier":"8199","nameIdentifierScheme":"WEKO"},{"nameIdentifier":"000005885823","nameIdentifierScheme":"CiNii ID","nameIdentifierURI":"http://ci.nii.ac.jp/nrid/000005885823"}],"names":[{"name":"KATO, Michihisa"}]}]},"item_5_heading_23":{"attribute_name":"見出し","attribute_value_mlt":[{"subitem_heading_banner_headline":"臨床経験","subitem_heading_language":"ja"}]},"item_5_publisher_8":{"attribute_name":"出版者","attribute_value_mlt":[{"subitem_publisher":"徳島赤十字病院"}]},"item_5_relation_17":{"attribute_name":"関連サイト","attribute_value_mlt":[{"subitem_relation_name":[{"subitem_relation_name_text":"徳島赤十字病院"}],"subitem_relation_type_id":{"subitem_relation_type_id_text":"http://www.tokushima-med.jrc.or.jp/hospital/medical/2007pdf/032.pdf","subitem_relation_type_select":"URI"}}]},"item_5_source_id_9":{"attribute_name":"ISSN","attribute_value_mlt":[{"subitem_source_identifier":"1346-9878","subitem_source_identifier_type":"ISSN"}]},"item_5_version_type_20":{"attribute_name":"著者版フラグ","attribute_value_mlt":[{"subitem_version_resource":"http://purl.org/coar/version/c_970fb48d4fbd8a85","subitem_version_type":"VoR"}]},"item_creator":{"attribute_name":"著者","attribute_type":"creator","attribute_value_mlt":[{"creatorNames":[{"creatorName":"加藤, 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