{"created":"2023-06-20T15:50:34.796577+00:00","id":3409,"links":{},"metadata":{"_buckets":{"deposit":"2df85e0a-0b84-4ebb-9f8c-022c4bdac9f0"},"_deposit":{"created_by":18,"id":"3409","owners":[18],"pid":{"revision_id":0,"type":"depid","value":"3409"},"status":"published"},"_oai":{"id":"oai:redcross.repo.nii.ac.jp:00003409","sets":["99:64:116"]},"author_link":["348","8097","8197","8098","6753","372","8196","6643","8198","8199","364"],"item_5_biblio_info_7":{"attribute_name":"書誌情報","attribute_value_mlt":[{"bibliographicIssueDates":{"bibliographicIssueDate":"2007-03-01","bibliographicIssueDateType":"Issued"},"bibliographicIssueNumber":"1","bibliographicPageEnd":"182","bibliographicPageStart":"178","bibliographicVolumeNumber":"12","bibliographic_titles":[{"bibliographic_title":"徳島赤十字病院医学雑誌"},{"bibliographic_title":"Tokushima Red Cross Hospital Medical Journal","bibliographic_titleLang":"en"}]}]},"item_5_description_5":{"attribute_name":"抄録","attribute_value_mlt":[{"subitem_description":"胸腹部大動脈瘤では，補助循環を用いずに大動脈単純遮断で手術を行うことがあり，その際には肝臓および腎臓への血流が一時的に遮断されるため，プロポフォールの血中濃度が大きく変化すると考えられる．今回我々は２症例で，大動脈単純遮断前後のプロポフォールの血漿中全濃度および非結合型濃度を測定し，予測血中濃度と比較検討したので報告する．麻酔導入後，プロポフォールは２mg/kg/hr の速度で持続投与した．大動脈単純遮断中にプロポフォールの血漿中全濃度および非結合型濃度が上昇し，血漿中全濃度は遮断前と比較しておよそ1.8倍に上昇した．遮断解除後には比較的速やかに低下し，遮断解除後30分から60分で遮断前の値に回復した．シミュレーションによる予測血中濃度と実測値の関連は，症例１では実測値がやや低めであったが，症例２ではよく一致しており，あらかじめプロポフォールの変化を予測することが可能と考えられた．","subitem_description_type":"Abstract"}]},"item_5_full_name_3":{"attribute_name":"著者別名","attribute_value_mlt":[{"nameIdentifiers":[{"nameIdentifierScheme":"WEKO"},{"nameIdentifierScheme":"CiNii ID","nameIdentifierURI":"http://ci.nii.ac.jp/nrid/000005885823"}],"names":[{"name":"KATO, Michihisa"}]}]},"item_5_heading_23":{"attribute_name":"見出し","attribute_value_mlt":[{"subitem_heading_banner_headline":"臨床経験","subitem_heading_language":"ja"}]},"item_5_publisher_8":{"attribute_name":"出版者","attribute_value_mlt":[{"subitem_publisher":"徳島赤十字病院"}]},"item_5_relation_17":{"attribute_name":"関連サイト","attribute_value_mlt":[{"subitem_relation_name":[{"subitem_relation_name_text":"徳島赤十字病院"}],"subitem_relation_type_id":{"subitem_relation_type_id_text":"http://www.tokushima-med.jrc.or.jp/hospital/medical/2007pdf/032.pdf","subitem_relation_type_select":"URI"}}]},"item_5_source_id_9":{"attribute_name":"ISSN","attribute_value_mlt":[{"subitem_source_identifier":"1346-9878","subitem_source_identifier_type":"ISSN"}]},"item_5_version_type_20":{"attribute_name":"著者版フラグ","attribute_value_mlt":[{"subitem_version_resource":"http://purl.org/coar/version/c_970fb48d4fbd8a85","subitem_version_type":"VoR"}]},"item_creator":{"attribute_name":"著者","attribute_type":"creator","attribute_value_mlt":[{"creatorNames":[{"creatorName":"加藤, 道久"}],"nameIdentifiers":[{},{}]},{"creatorNames":[{"creatorName":"甲藤, 貴子"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"若松, 成知"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":" 酒井, 陽子"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"郷, 律子"}],"nameIdentifiers":[{},{}]},{"creatorNames":[{"creatorName":"神山, 有史"}],"nameIdentifiers":[{},{}]},{"creatorNames":[{"creatorName":"高松, 誉明"}],"nameIdentifiers":[{},{}]},{"creatorNames":[{"creatorName":"福村, 好晃"}],"nameIdentifiers":[{},{}]},{"creatorNames":[{"creatorName":"石田, 志朗"}],"nameIdentifiers":[{},{}]},{"creatorNames":[{"creatorName":"岡野, 善郎"}],"nameIdentifiers":[{}]}]},"item_files":{"attribute_name":"ファイル情報","attribute_type":"file","attribute_value_mlt":[{"accessrole":"open_date","date":[{"dateType":"Available","dateValue":"2013-05-06"}],"displaytype":"simple","filename":"trchmj1201_178-182.pdf","filesize":[{"value":"693.5 kB"}],"format":"application/pdf","licensetype":"license_note","mimetype":"application/pdf","url":{"label":"pdf002182","url":"https://redcross.repo.nii.ac.jp/record/3409/files/trchmj1201_178-182.pdf"},"version_id":"cabff709-020f-415b-ae07-eb6c6a3ade59"}]},"item_keyword":{"attribute_name":"キーワード","attribute_value_mlt":[{"subitem_subject":"プロポフォール","subitem_subject_scheme":"Other"},{"subitem_subject":"胸腹部大動脈瘤","subitem_subject_scheme":"Other"},{"subitem_subject":"血中濃度","subitem_subject_scheme":"Other"}]},"item_language":{"attribute_name":"言語","attribute_value_mlt":[{"subitem_language":"jpn"}]},"item_resource_type":{"attribute_name":"資源タイプ","attribute_value_mlt":[{"resourcetype":"technical report"}]},"item_title":"胸腹部大動脈瘤手術症例のプロポフォール血漿中濃度の変化","item_titles":{"attribute_name":"タイトル","attribute_value_mlt":[{"subitem_title":"胸腹部大動脈瘤手術症例のプロポフォール血漿中濃度の変化"}]},"item_type_id":"5","owner":"18","path":["116"],"pubdate":{"attribute_name":"公開日","attribute_value":"2013-05-06"},"publish_date":"2013-05-06","publish_status":"0","recid":"3409","relation_version_is_last":true,"title":["胸腹部大動脈瘤手術症例のプロポフォール血漿中濃度の変化"],"weko_creator_id":"18","weko_shared_id":18},"updated":"2023-06-20T22:03:51.030728+00:00"}