{"created":"2023-06-20T15:50:32.473931+00:00","id":3346,"links":{},"metadata":{"_buckets":{"deposit":"5a03c69e-51f9-4535-a27d-90d3a59c36a4"},"_deposit":{"created_by":28,"id":"3346","owners":[28],"pid":{"revision_id":0,"type":"depid","value":"3346"},"status":"published"},"_oai":{"id":"oai:redcross.repo.nii.ac.jp:00003346","sets":["172:173:175"]},"author_link":["7967","7944","7977","7975","7972","7949","7978","7976","7943","7965","7961","7951","7969","7966","7970","7964","7959","7947","7955","7952","7956","7974","7950","7941","7957","7942","7968","7960","7948","7953","7963","7971","7954","7958","7973","7946","7945","7962"],"item_10001_biblio_info_7":{"attribute_name":"書誌情報","attribute_value_mlt":[{"bibliographicIssueDates":{"bibliographicIssueDate":"2012-12","bibliographicIssueDateType":"Issued"},"bibliographicPageEnd":"72","bibliographicPageStart":"63","bibliographicVolumeNumber":"30","bibliographic_titles":[{"bibliographic_title":"日本赤十字社和歌山医療センター医学雑誌"},{"bibliographic_title":"Medical Journal of Japanese Red Cross Society Wakayama Medical Center","bibliographic_titleLang":"en"}]}]},"item_10001_description_5":{"attribute_name":"抄録","attribute_value_mlt":[{"subitem_description":"C型慢性肝炎genotype1型高ウイルス量、初回治療53症例に対して二重濾過膜血漿交換療法(Double Filtration Plasmapheresis:DFPP)を併用したペグインターフェロン+リバビリン(PEG-IFN+RBV)治療を行い、治療効果と安全性について検討した。Early virological response(EVR)率はDFPP群76.7%、非DFPP群56.3%であり、DFPP群で有意に高い結果となった(P<0.05)。さらにEVR症例におけるその後のウイルス持続陰性化(sustained virological response:SVR)到達率は、DFPP群77%、非DFPP群73.2%であり両群間で同等と考えられた。したがってDFPPを併用しEVR率を高める事によって、最終的なSVRの向上に寄与する可能性が示唆された。また高齢患者に対しても施行基準を遵守することで、重篤な副作用を認めず安全に施行できた。","subitem_description_type":"Abstract"}]},"item_10001_full_name_3":{"attribute_name":"著者別名","attribute_value_mlt":[{"nameIdentifiers":[{}],"names":[{"name":"Nakatani, Yasuki"}]},{"nameIdentifiers":[{}],"names":[{"name":"Azuma, Shunjiro"}]},{"nameIdentifiers":[{}],"names":[{"name":"Noguchi, Mio"}]},{"nameIdentifiers":[{}],"names":[{"name":"Yabuuchi , Yohei"}]},{"nameIdentifiers":[{}],"names":[{"name":"Matsumoto, Hisakazu"}]},{"nameIdentifiers":[{}],"names":[{"name":"Ohta, Sakiko"}]},{"nameIdentifiers":[{}],"names":[{"name":"Nobuoka, Miyu"}]},{"nameIdentifiers":[{}],"names":[{"name":"Mikami, Takeo"}]},{"nameIdentifiers":[{}],"names":[{"name":"Iwagami, Hiroyoshi"}]},{"nameIdentifiers":[{}],"names":[{"name":"Tsuda, Motoyuki"}]},{"nameIdentifiers":[{}],"names":[{"name":"Minaga, Kosuke"}]},{"nameIdentifiers":[{}],"names":[{"name":"Lee, Minami"}]},{"nameIdentifiers":[{}],"names":[{"name":"Nakamura, Fumiyasu"}]},{"nameIdentifiers":[{}],"names":[{"name":"Taniguchi, Yohei"}]},{"nameIdentifiers":[{}],"names":[{"name":"Akamatsu, Takuji"}]},{"nameIdentifiers":[{}],"names":[{"name":"Seta, Takeshi"}]},{"nameIdentifiers":[{}],"names":[{"name":"Urai, Shunji"}]},{"nameIdentifiers":[{}],"names":[{"name":"Uenoyama, Yoshito"}]},{"nameIdentifiers":[{}],"names":[{"name":"Yamashita, Yukitaka"}]}]},"item_10001_publisher_8":{"attribute_name":"出版者","attribute_value_mlt":[{"subitem_publisher":"日本赤十字社和歌山医療センター"}]},"item_10001_source_id_9":{"attribute_name":"ISSN","attribute_value_mlt":[{"subitem_source_identifier":"1341-9927","subitem_source_identifier_type":"ISSN"}]},"item_10001_version_type_20":{"attribute_name":"著者版フラグ","attribute_value_mlt":[{"subitem_version_resource":"http://purl.org/coar/version/c_970fb48d4fbd8a85","subitem_version_type":"VoR"}]},"item_creator":{"attribute_name":"著者","attribute_type":"creator","attribute_value_mlt":[{"creatorNames":[{"creatorName":"中谷, 泰樹"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"東, 俊二郎"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"野口, 未央"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"籔内, 洋平"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"松本, 久和"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"太田, 彩貴子"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"信岡, 未由"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"三上, 貴生"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"岩上, 裕吉"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"津田, 喬之"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"三長, 孝輔"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"李, 宗南"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"中村, 文保"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"谷口, 洋平"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"赤松, 拓司"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"瀬田, 剛史"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"浦井, 俊二"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"上野山, 義人"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"山下, 幸孝"}],"nameIdentifiers":[{}]}]},"item_files":{"attribute_name":"ファイル情報","attribute_type":"file","attribute_value_mlt":[{"accessrole":"open_date","date":[{"dateType":"Available","dateValue":"2013-12-01"}],"displaytype":"simple","filename":"10（中谷泰樹）.pdf","filesize":[{"value":"1.2 MB"}],"format":"application/pdf","licensetype":"license_note","mimetype":"application/pdf","url":{"label":"Wakayama30_10","url":"https://redcross.repo.nii.ac.jp/record/3346/files/10（中谷泰樹）.pdf"},"version_id":"cb04fe55-cdbd-4680-9621-3ee61fcdd93c"}]},"item_keyword":{"attribute_name":"キーワード","attribute_value_mlt":[{"subitem_subject":"二重濾過血漿交換法（DFPP）","subitem_subject_scheme":"Other"},{"subitem_subject":"VRAD","subitem_subject_scheme":"Other"},{"subitem_subject":"Genotype1型高ウイルス量C型慢性肝炎","subitem_subject_scheme":"Other"},{"subitem_subject":"ウイルス遺伝子","subitem_subject_scheme":"Other"},{"subitem_subject":"遺伝子型","subitem_subject_scheme":"Other"},{"subitem_subject":"慢性肝炎","subitem_subject_scheme":"Other"},{"subitem_subject":"リバビリン併用療法","subitem_subject_scheme":"Other"},{"subitem_subject":"ペグインターフェロン","subitem_subject_scheme":"Other"},{"subitem_subject":"二重濾過血漿交換","subitem_subject_scheme":"Other"},{"subitem_subject":"Ribavirin","subitem_subject_language":"en","subitem_subject_scheme":"Other"},{"subitem_subject":"Peginterferon Alfa-2b","subitem_subject_language":"en","subitem_subject_scheme":"Other"},{"subitem_subject":"Virus Removal and Eradication by DFPP:VRAD","subitem_subject_language":"en","subitem_subject_scheme":"Other"},{"subitem_subject":"Double Filtration Plasmapheresisi:DFPP","subitem_subject_language":"en","subitem_subject_scheme":"Other"}]},"item_language":{"attribute_name":"言語","attribute_value_mlt":[{"subitem_language":"jpn"}]},"item_resource_type":{"attribute_name":"資源タイプ","attribute_value_mlt":[{"resourcetype":"journal article","resourceuri":"http://purl.org/coar/resource_type/c_6501"}]},"item_title":"Genotype 1型高ウイルス量C型慢性肝炎患者(初回治療例)における二重濾過血漿交換法(DFPP)併用ペグインターフェロン+リバビリン(PEG-IFN+RBV)療法の有効性に関する検討","item_titles":{"attribute_name":"タイトル","attribute_value_mlt":[{"subitem_title":"Genotype 1型高ウイルス量C型慢性肝炎患者(初回治療例)における二重濾過血漿交換法(DFPP)併用ペグインターフェロン+リバビリン(PEG-IFN+RBV)療法の有効性に関する検討"}]},"item_type_id":"10001","owner":"28","path":["175"],"pubdate":{"attribute_name":"公開日","attribute_value":"2013-04-24"},"publish_date":"2013-04-24","publish_status":"0","recid":"3346","relation_version_is_last":true,"title":["Genotype 1型高ウイルス量C型慢性肝炎患者(初回治療例)における二重濾過血漿交換法(DFPP)併用ペグインターフェロン+リバビリン(PEG-IFN+RBV)療法の有効性に関する検討"],"weko_creator_id":"28","weko_shared_id":-1},"updated":"2023-06-20T19:30:54.550522+00:00"}