{"created":"2023-06-20T15:50:32.344530+00:00","id":3343,"links":{},"metadata":{"_buckets":{"deposit":"ed950329-7513-464c-87d7-2100d48eac6e"},"_deposit":{"created_by":28,"id":"3343","owners":[28],"pid":{"revision_id":0,"type":"depid","value":"3343"},"status":"published"},"_oai":{"id":"oai:redcross.repo.nii.ac.jp:00003343","sets":["172:173:175"]},"author_link":["7884","7890","7885","7892","7896","7894","7889","7888","7893","7895","7887","7886","7897","7891"],"item_10001_biblio_info_7":{"attribute_name":"書誌情報","attribute_value_mlt":[{"bibliographicIssueDates":{"bibliographicIssueDate":"2012-12","bibliographicIssueDateType":"Issued"},"bibliographicPageEnd":"47","bibliographicPageStart":"43","bibliographicVolumeNumber":"30","bibliographic_titles":[{"bibliographic_title":"日本赤十字社和歌山医療センター医学雑誌"},{"bibliographic_title":"Medical Journal of Japanese Red Cross Society Wakayama Medical Center","bibliographic_titleLang":"en"}]}]},"item_10001_description_5":{"attribute_name":"抄録","attribute_value_mlt":[{"subitem_description":"高圧酸素療法は広範な分野において適応され重用されている治療法である。副作用についても比較的少ないとされているが、一度発症した場合、重篤な症状を呈することがある。今回われわれは高圧酸素療法の副作用の一つとされている脳酸素中毒様症状を呈した1例を経験した。症例は87歳、男性、下顎左側犬歯および第一小臼歯の疼痛を主訴に当科受診した。抜歯適応歯であったが既往である前立腺がんの治療のためゾレドロン酸(ゾメタ)の投与歴があったためビスフォスホネート関連顎骨壊死予防のため高圧酸素療法併用とした。しかしながら、高圧酸素療法7回目施行中に視野狭窄、眩暈、全身痙攣といった脳酸素中毒様症状を呈した。翌日には症状は消失したものの、高圧酸素療法は中止し、経過良好のため退院した。本症状の原因としてペニシリン系抗菌薬の関与が示唆された。ビスフォスホネート関連顎骨壊死予防のためペニシリン系抗菌薬は頻繁に使用されているが、脳酸素中毒のリスクを上昇させる可能性があるため今後、投与すべき抗菌薬を再考する必要があると考える。","subitem_description_type":"Abstract"}]},"item_10001_full_name_3":{"attribute_name":"著者別名","attribute_value_mlt":[{"nameIdentifiers":[{}],"names":[{"name":"Shimada, Takuya"}]},{"nameIdentifiers":[{},{}],"names":[{"name":"Taga, Tomoharu"}]},{"nameIdentifiers":[{}],"names":[{"name":"Tanaka, Katsuhiko"}]},{"nameIdentifiers":[{}],"names":[{"name":"Nishino, Ryousuke"}]},{"nameIdentifiers":[{}],"names":[{"name":"Miyamoto, Asuka"}]},{"nameIdentifiers":[{}],"names":[{"name":"Senga, Hitomi"}]},{"nameIdentifiers":[{}],"names":[{"name":"Tsujimoto, Toshihide"}]}]},"item_10001_publisher_8":{"attribute_name":"出版者","attribute_value_mlt":[{"subitem_publisher":"日本赤十字社和歌山医療センター"}]},"item_10001_source_id_9":{"attribute_name":"ISSN","attribute_value_mlt":[{"subitem_source_identifier":"1341-9927","subitem_source_identifier_type":"ISSN"}]},"item_10001_version_type_20":{"attribute_name":"著者版フラグ","attribute_value_mlt":[{"subitem_version_resource":"http://purl.org/coar/version/c_970fb48d4fbd8a85","subitem_version_type":"VoR"}]},"item_creator":{"attribute_name":"著者","attribute_type":"creator","attribute_value_mlt":[{"creatorNames":[{"creatorName":"島田, 拓矢"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"多賀, 智治"}],"nameIdentifiers":[{},{}]},{"creatorNames":[{"creatorName":"田中, 克彦"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"西野, 亮輔"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"宮本, 明日香"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"千賀, 人美"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"辻本, 登志英"}],"nameIdentifiers":[{}]}]},"item_files":{"attribute_name":"ファイル情報","attribute_type":"file","attribute_value_mlt":[{"accessrole":"open_date","date":[{"dateType":"Available","dateValue":"2013-12-01"}],"displaytype":"simple","filename":"07（島田拓矢）.pdf","filesize":[{"value":"644.1 kB"}],"format":"application/pdf","licensetype":"license_note","mimetype":"application/pdf","url":{"label":"Wakayama30_07","url":"https://redcross.repo.nii.ac.jp/record/3343/files/07（島田拓矢）.pdf"},"version_id":"48d978c4-89ae-46e0-a2c8-75132a9cf1e4"}]},"item_keyword":{"attribute_name":"キーワード","attribute_value_mlt":[{"subitem_subject":"高圧酸素療法","subitem_subject_scheme":"Other"},{"subitem_subject":"酸素中毒","subitem_subject_scheme":"Other"},{"subitem_subject":"副作用","subitem_subject_scheme":"Other"},{"subitem_subject":"ビスフォスフォネート関連顎骨壊死","subitem_subject_scheme":"Other"},{"subitem_subject":"ビスホスホネート系薬剤関連顎骨壊死","subitem_subject_scheme":"Other"},{"subitem_subject":"ペニシリン","subitem_subject_scheme":"Other"},{"subitem_subject":"抗菌薬","subitem_subject_scheme":"Other"}]},"item_language":{"attribute_name":"言語","attribute_value_mlt":[{"subitem_language":"jpn"}]},"item_resource_type":{"attribute_name":"資源タイプ","attribute_value_mlt":[{"resourcetype":"journal article","resourceuri":"http://purl.org/coar/resource_type/c_6501"}]},"item_title":"高圧酸素療法中に脳酸素中毒をきたした1例","item_titles":{"attribute_name":"タイトル","attribute_value_mlt":[{"subitem_title":"高圧酸素療法中に脳酸素中毒をきたした1例"}]},"item_type_id":"10001","owner":"28","path":["175"],"pubdate":{"attribute_name":"公開日","attribute_value":"2013-04-24"},"publish_date":"2013-04-24","publish_status":"0","recid":"3343","relation_version_is_last":true,"title":["高圧酸素療法中に脳酸素中毒をきたした1例"],"weko_creator_id":"28","weko_shared_id":-1},"updated":"2023-06-20T19:30:47.963245+00:00"}