{"created":"2023-06-20T15:50:31.545986+00:00","id":3314,"links":{},"metadata":{"_buckets":{"deposit":"19c7b480-e809-4d0e-9e8c-1c237cc5d319"},"_deposit":{"created_by":18,"id":"3314","owners":[18],"pid":{"revision_id":0,"type":"depid","value":"3314"},"status":"published"},"_oai":{"id":"oai:redcross.repo.nii.ac.jp:00003314","sets":["99:64:116"]},"author_link":["296","298","132","286","285","297","300","295","314","294","301","131","299","6880"],"item_10002_biblio_info_7":{"attribute_name":"書誌情報","attribute_value_mlt":[{"bibliographicIssueDates":{"bibliographicIssueDate":"2007-03-01","bibliographicIssueDateType":"Issued"},"bibliographicIssueNumber":"1","bibliographicPageEnd":"24","bibliographicPageStart":"20","bibliographicVolumeNumber":"12","bibliographic_titles":[{"bibliographic_title":"徳島赤十字病院医学雑誌"},{"bibliographic_title":"Tokushima Red Cross Hospital Medical Journal","bibliographic_titleLang":"en"}]}]},"item_10002_description_5":{"attribute_name":"抄録","attribute_value_mlt":[{"subitem_description":"背景：心不全に対するβ 遮断薬療法は有用であるが，症例によっては副作用のために投与中止せざるを得ない．各種パラメータを測定し，カルベジロール投与における予後不良の予測因子を検討した．\r\n方法と結果：2003年7月～2005年6月に当院に入院した重症心不全，連続10例を対象とした．カルベジロールの初期投与量は2.5mg／日で，4～8週間かけて徐々に増量した．全例で導入可能であり，10mg／日で12ヵ月間の投与後，エコーにて心機能を評価した．心不全の悪化のため，3例（30％）で投与を中止した．中止例では年齢が有意に高かった（79.3±2.3歳対59.3±11.5歳，p＜0.05）．導入前の左室駆出率やその他の各種パラメータでは，副作用の出現を予測することはできなかったが，導入後に左室拡大を認める症例は予後不良であった（左室拡張末期径の変化：12.0±11.3mm 対－2.0±7.6mm，p＝0.05）．\r\n結論：重症心不全患者に対してカルベジロールは安全に導入可能であり，年齢のみが予後不良の予測因子であった．","subitem_description_type":"Abstract"}]},"item_10002_heading_23":{"attribute_name":"見出し","attribute_value_mlt":[{"subitem_heading_banner_headline":"原著","subitem_heading_language":"ja"}]},"item_10002_publisher_8":{"attribute_name":"出版者","attribute_value_mlt":[{"subitem_publisher":"徳島赤十字病院"}]},"item_10002_relation_17":{"attribute_name":"関連サイト","attribute_value_mlt":[{"subitem_relation_name":[{"subitem_relation_name_text":"徳島赤十字病院"}],"subitem_relation_type_id":{}}]},"item_10002_source_id_9":{"attribute_name":"ISSN","attribute_value_mlt":[{"subitem_source_identifier":"1346-9878 ","subitem_source_identifier_type":"ISSN"}]},"item_10002_version_type_20":{"attribute_name":"著者版フラグ","attribute_value_mlt":[{"subitem_version_resource":"http://purl.org/coar/version/c_970fb48d4fbd8a85","subitem_version_type":"VoR"}]},"item_creator":{"attribute_name":"著者","attribute_type":"creator","attribute_value_mlt":[{"creatorNames":[{"creatorName":"當別當, 洋平"}],"nameIdentifiers":[{},{}]},{"creatorNames":[{"creatorName":"日浅, 芳一"}],"nameIdentifiers":[{},{}]},{"creatorNames":[{"creatorName":"鈴木, 直紀"}],"nameIdentifiers":[{},{}]},{"creatorNames":[{"creatorName":"陳, 博敏"}],"nameIdentifiers":[{},{}]},{"creatorNames":[{"creatorName":"宮崎, 晋一郎"}],"nameIdentifiers":[{},{}]},{"creatorNames":[{"creatorName":"馬原, 啓太郎"}],"nameIdentifiers":[{},{}]},{"creatorNames":[{"creatorName":"宮島, 等"}],"nameIdentifiers":[{},{}]},{"creatorNames":[{"creatorName":"小倉, 理代"}],"nameIdentifiers":[{},{}]},{"creatorNames":[{"creatorName":"弓場, 健一郎"}],"nameIdentifiers":[{},{}]},{"creatorNames":[{"creatorName":"高橋, 健文"}],"nameIdentifiers":[{},{}]},{"creatorNames":[{"creatorName":"細川, 忍"}],"nameIdentifiers":[{},{}]},{"creatorNames":[{"creatorName":"岸, 宏一"}],"nameIdentifiers":[{},{}]},{"creatorNames":[{"creatorName":"大谷, 龍治"}],"nameIdentifiers":[{},{}]}]},"item_files":{"attribute_name":"ファイル情報","attribute_type":"file","attribute_value_mlt":[{"accessrole":"open_date","date":[{"dateType":"Available","dateValue":"2013-04-15"}],"displaytype":"simple","filename":"trchmj1201_20-24.pdf","filesize":[{"value":"693.1 kB"}],"format":"application/pdf","licensetype":"license_note","mimetype":"application/pdf","url":{"label":"pdf002121","url":"https://redcross.repo.nii.ac.jp/record/3314/files/trchmj1201_20-24.pdf"},"version_id":"11b95976-ef7a-473e-b8bb-8a5ea5295953"}]},"item_keyword":{"attribute_name":"キーワード","attribute_value_mlt":[{"subitem_subject":"心不全","subitem_subject_scheme":"Other"},{"subitem_subject":"β遮断薬","subitem_subject_scheme":"Other"},{"subitem_subject":"左室拡大","subitem_subject_scheme":"Other"},{"subitem_subject":"予後","subitem_subject_scheme":"Other"},{"subitem_subject":"心エコー","subitem_subject_scheme":"Other"},{"subitem_subject":"heart failure","subitem_subject_language":"en","subitem_subject_scheme":"Other"},{"subitem_subject":"Beta-Adrenoceptor antagonists","subitem_subject_language":"en","subitem_subject_scheme":"Other"},{"subitem_subject":"left ventricular dilatation","subitem_subject_language":"en","subitem_subject_scheme":"Other"},{"subitem_subject":"prognosis","subitem_subject_language":"en","subitem_subject_scheme":"Other"},{"subitem_subject":"echocardiography","subitem_subject_language":"en","subitem_subject_scheme":"Other"}]},"item_language":{"attribute_name":"言語","attribute_value_mlt":[{"subitem_language":"jpn"}]},"item_resource_type":{"attribute_name":"資源タイプ","attribute_value_mlt":[{"resourcetype":"departmental bulletin paper","resourceuri":"http://purl.org/coar/resource_type/c_6501"}]},"item_title":"重症心不全に対するβ遮断薬（カルベジロール）至適投与の指標について","item_titles":{"attribute_name":"タイトル","attribute_value_mlt":[{"subitem_title":"重症心不全に対するβ遮断薬（カルベジロール）至適投与の指標について"},{"subitem_title":"Optimizing Treatment of Beta-Adrenoceptor Antagonists （Carvedilol）in Patients with Severe Heart Failure","subitem_title_language":"en"}]},"item_type_id":"10002","owner":"18","path":["116"],"pubdate":{"attribute_name":"公開日","attribute_value":"2013-04-15"},"publish_date":"2013-04-15","publish_status":"0","recid":"3314","relation_version_is_last":true,"title":["重症心不全に対するβ遮断薬（カルベジロール）至適投与の指標について"],"weko_creator_id":"18","weko_shared_id":18},"updated":"2023-06-20T22:02:04.849221+00:00"}