{"created":"2023-06-20T15:50:31.454921+00:00","id":3312,"links":{},"metadata":{"_buckets":{"deposit":"4059fb56-d1ab-4b34-b9ee-2b89386a44e5"},"_deposit":{"created_by":18,"id":"3312","owners":[18],"pid":{"revision_id":0,"type":"depid","value":"3312"},"status":"published"},"_oai":{"id":"oai:redcross.repo.nii.ac.jp:00003312","sets":["99:64:115"]},"author_link":["7662","449","7663"],"item_10002_biblio_info_7":{"attribute_name":"書誌情報","attribute_value_mlt":[{"bibliographicIssueDates":{"bibliographicIssueDate":"2008-03-01","bibliographicIssueDateType":"Issued"},"bibliographicIssueNumber":"1","bibliographicPageEnd":"161","bibliographicPageStart":"158","bibliographicVolumeNumber":"13","bibliographic_titles":[{"bibliographic_title":"徳島赤十字病院医学雑誌"},{"bibliographic_title":"Tokushima Red Cross Hospital Medical Journal","bibliographic_titleLang":"en"}]}]},"item_10002_description_5":{"attribute_name":"抄録","attribute_value_mlt":[{"subitem_description":"当院で2006年9月1日から2007年8月31日までの期間で，喀痰からメチシリン耐性黄色ブドウ球菌（MRSA）が検出された17名について，投与が中止された6名を無効群として分別し，バンコマイシン（VCM）の投与歴を基に2社の血中薬物濃度測定（TDM）ソフトで解析を行い比較した．母集団パラメータが異なることからソフト間には推定値に差がある．MEEK-TDM（明治）では最大血中濃度（Cmax）は低めに，最小血中濃度（Cmin）は高めに推定された．MEEK-TDM では，Cmax を40～45μg/mL，Cmin を10～15μg/mL を目標に投与計画を行った場合，安全な初期投与設計となると思われる．有効群と無効群を比較して，無効群が高齢で，24時間の血中濃度‐時間曲線下面積（AUC24）は平均493μg/mL・hr と高めであり投与直前の血中濃度も平均11.5μg/mL と高値であった．","subitem_description_type":"Abstract"}]},"item_10002_heading_23":{"attribute_name":"見出し","attribute_value_mlt":[{"subitem_heading_banner_headline":"臨床経験","subitem_heading_language":"ja"}]},"item_10002_publisher_8":{"attribute_name":"出版者","attribute_value_mlt":[{"subitem_publisher":"徳島赤十字病院"}]},"item_10002_relation_17":{"attribute_name":"関連サイト","attribute_value_mlt":[{"subitem_relation_name":[{"subitem_relation_name_text":"徳島赤十字病院"}],"subitem_relation_type_id":{}}]},"item_10002_source_id_9":{"attribute_name":"ISSN","attribute_value_mlt":[{"subitem_source_identifier":"1346-9878 ","subitem_source_identifier_type":"ISSN"}]},"item_10002_version_type_20":{"attribute_name":"著者版フラグ","attribute_value_mlt":[{"subitem_version_resource":"http://purl.org/coar/version/c_970fb48d4fbd8a85","subitem_version_type":"VoR"}]},"item_creator":{"attribute_name":"著者","attribute_type":"creator","attribute_value_mlt":[{"creatorNames":[{"creatorName":"竹内, 隆文"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"山川, 和宣"}],"nameIdentifiers":[{},{}]}]},"item_files":{"attribute_name":"ファイル情報","attribute_type":"file","attribute_value_mlt":[{"accessrole":"open_date","date":[{"dateType":"Available","dateValue":"2013-04-11"}],"displaytype":"simple","filename":"trchmj1301_158-161.pdf","filesize":[{"value":"1.3 MB"}],"format":"application/pdf","licensetype":"license_note","mimetype":"application/pdf","url":{"label":"pdf002119","url":"https://redcross.repo.nii.ac.jp/record/3312/files/trchmj1301_158-161.pdf"},"version_id":"77bab5fc-e55a-44a0-8254-e71330220551"}]},"item_keyword":{"attribute_name":"キーワード","attribute_value_mlt":[{"subitem_subject":"バンコマイシン","subitem_subject_scheme":"Other"},{"subitem_subject":"TDM","subitem_subject_scheme":"Other"},{"subitem_subject":"AUC","subitem_subject_scheme":"Other"},{"subitem_subject":"MIC","subitem_subject_scheme":"Other"},{"subitem_subject":"Vancomycin","subitem_subject_language":"en","subitem_subject_scheme":"Other"},{"subitem_subject":"TDM","subitem_subject_language":"en","subitem_subject_scheme":"Other"},{"subitem_subject":"AUC","subitem_subject_language":"en","subitem_subject_scheme":"Other"},{"subitem_subject":"MIC","subitem_subject_language":"en","subitem_subject_scheme":"Other"}]},"item_language":{"attribute_name":"言語","attribute_value_mlt":[{"subitem_language":"jpn"}]},"item_resource_type":{"attribute_name":"資源タイプ","attribute_value_mlt":[{"resourcetype":"departmental bulletin paper","resourceuri":"http://purl.org/coar/resource_type/c_6501"}]},"item_title":"当院でのバンコマイシン血中薬物濃度測定解析ソフトの使用報告","item_titles":{"attribute_name":"タイトル","attribute_value_mlt":[{"subitem_title":"当院でのバンコマイシン血中薬物濃度測定解析ソフトの使用報告"},{"subitem_title":"Computer Programs for Analysis of Blood Vancomycin Level Used at Our Hospital","subitem_title_language":"en"}]},"item_type_id":"10002","owner":"18","path":["115"],"pubdate":{"attribute_name":"公開日","attribute_value":"2013-04-11"},"publish_date":"2013-04-11","publish_status":"0","recid":"3312","relation_version_is_last":true,"title":["当院でのバンコマイシン血中薬物濃度測定解析ソフトの使用報告"],"weko_creator_id":"18","weko_shared_id":18},"updated":"2023-06-20T22:02:01.093122+00:00"}