{"created":"2023-06-20T16:00:26.767935+00:00","id":18870,"links":{},"metadata":{"_buckets":{"deposit":"d3eea41a-e631-48d0-9296-9eb52228015e"},"_deposit":{"created_by":41,"id":"18870","owners":[41],"pid":{"revision_id":0,"type":"depid","value":"18870"},"status":"published"},"_oai":{"id":"oai:redcross.repo.nii.ac.jp:00018870","sets":["340:341:733"]},"author_link":["70766","70768","70769","70767"],"item_10001_biblio_info_7":{"attribute_name":"書誌情報","attribute_value_mlt":[{"bibliographicIssueDates":{"bibliographicIssueDate":"2023-03-31","bibliographicIssueDateType":"Issued"},"bibliographicIssueNumber":"1","bibliographicPageEnd":"114","bibliographicPageStart":"109","bibliographicVolumeNumber":"27","bibliographic_titles":[{"bibliographic_title":"高知赤十字病院医学雑誌"}]}]},"item_10001_description_5":{"attribute_name":"抄録","attribute_value_mlt":[{"subitem_description":"80 歳代，女性．血管免疫芽球性 T 細胞性リンパ腫（ Angio immunoblastic T-cell lymphoma： AITL）に対して CHOP 療法で寛解したが翌年再発．AITL は治療抵抗性となり，緩和療法として自宅療養していた．X 年6月21日にファイザー社のコロナウイルス修飾ウリジン RNA ワクチン1回目の接種を受けた．24 日に右肘腫脹，27 日から食欲低下，尿量減少を認め，28 日から見当識障害が見られ同日受診した．頭部 MRI 検査では右後頭葉に急性の梗塞巣を認めた．血小板減少と炎症所見の増悪がみられ，右下肢膝窩静脈の血栓，右肘頭滑液包炎を認めた．血小板減少を伴う血栓症（Thrombosis with Thrombocytopenia \nSyndrome：TTS）の発症を疑った．抗菌薬投与と，TTS に対してアルガトロバンの投与後，エドキサバンの内服に変更し，血液凝固異常は改善した．ファイザー社のコロナウイルス修飾ウリジン RNA ワクチンでは，ワクチン惹起性の TTS（VITTS）の報告例はないが，血小板減少を来した症例は報告されている．本症例は基礎疾患の AITL に右肘頭滑液包炎を\n併発した可能性も否定できないが，ワクチン接種後に TTS を発症しており興味深い経過であった．","subitem_description_type":"Abstract"}]},"item_10001_publisher_8":{"attribute_name":"出版者","attribute_value_mlt":[{"subitem_publisher":"高知赤十字病院"}]},"item_10001_rights_15":{"attribute_name":"権利","attribute_value_mlt":[{"subitem_rights":"高知赤十字病院"}]},"item_10001_source_id_9":{"attribute_name":"ISSN","attribute_value_mlt":[{"subitem_source_identifier":"0919-7427","subitem_source_identifier_type":"ISSN"}]},"item_creator":{"attribute_name":"著者","attribute_type":"creator","attribute_value_mlt":[{"creatorNames":[{"creatorName":"山中, 絵里加"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"上村, 宗範"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"溝渕, 樹"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"佐原, 和真"}],"nameIdentifiers":[{}]}]},"item_files":{"attribute_name":"ファイル情報","attribute_type":"file","attribute_value_mlt":[{"accessrole":"open_date","date":[{"dateType":"Available","dateValue":"2023-06-02"}],"displaytype":"simple","filename":"初期臨床研修医 山中絵里加.pdf","filesize":[{"value":"1.0 MB"}],"format":"application/pdf","licensetype":"license_note","mimetype":"application/pdf","url":{"label":"高知赤十字病院医学雑誌Vol.27-23  ","url":"https://redcross.repo.nii.ac.jp/record/18870/files/初期臨床研修医 山中絵里加.pdf"},"version_id":"f98a8a95-11d3-4cb4-bba7-6b91beaff03a"}]},"item_keyword":{"attribute_name":"キーワード","attribute_value_mlt":[{"subitem_subject":"新型コロナウイルスワクチン","subitem_subject_scheme":"Other"},{"subitem_subject":"血小板減少を伴う血栓症（TTS）","subitem_subject_scheme":"Other"},{"subitem_subject":"抗 PF4抗体","subitem_subject_scheme":"Other"}]},"item_language":{"attribute_name":"言語","attribute_value_mlt":[{"subitem_language":"jpn"}]},"item_resource_type":{"attribute_name":"資源タイプ","attribute_value_mlt":[{"resourcetype":"journal article","resourceuri":"http://purl.org/coar/resource_type/c_6501"}]},"item_title":"新型コロナウイルスワクチン接種後に発症した 血小板減少を伴う血栓症の一例","item_titles":{"attribute_name":"タイトル","attribute_value_mlt":[{"subitem_title":"新型コロナウイルスワクチン接種後に発症した 血小板減少を伴う血栓症の一例"}]},"item_type_id":"10001","owner":"41","path":["733"],"pubdate":{"attribute_name":"公開日","attribute_value":"2023-06-02"},"publish_date":"2023-06-02","publish_status":"0","recid":"18870","relation_version_is_last":true,"title":["新型コロナウイルスワクチン接種後に発症した 血小板減少を伴う血栓症の一例"],"weko_creator_id":"41","weko_shared_id":-1},"updated":"2023-06-20T17:34:25.748059+00:00"}