{"created":"2023-06-20T16:00:09.355207+00:00","id":18439,"links":{},"metadata":{"_buckets":{"deposit":"e156d646-e9f0-40f3-93ee-04e73adf9fdf"},"_deposit":{"created_by":29,"id":"18439","owners":[29],"pid":{"revision_id":0,"type":"depid","value":"18439"},"status":"published"},"_oai":{"id":"oai:redcross.repo.nii.ac.jp:00018439","sets":["95:28:407"]},"author_link":["50998","3543","69646","44373"],"item_10002_biblio_info_7":{"attribute_name":"書誌情報","attribute_value_mlt":[{"bibliographicIssueDates":{"bibliographicIssueDate":"2005-12-01","bibliographicIssueDateType":"Issued"},"bibliographicIssueNumber":"1","bibliographicPageEnd":"90","bibliographicPageStart":"85","bibliographicVolumeNumber":"25","bibliographic_titles":[{"bibliographic_title":"静岡赤十字病院研究報"},{"bibliographic_title":"Journal of Japanese Red Cross Shizuoka Hospital","bibliographic_titleLang":"en"}]}]},"item_10002_description_5":{"attribute_name":"抄録","attribute_value_mlt":[{"subitem_description":"症例は54歳,女性.主訴は手指壊疽.平成13年12月発症の強皮症(びまん型),間質性肺炎でステロイド,シクロスポリン,D-ペニシラミンなどで加療されていたが,治療抵抗性で皮膚硬化,手指壊疽が悪化し,入退院を繰り返していた.平成17年1月,右III,IV指尖の壊疽が進行したため入院.Prostaglandin E1,Prostaglandin I2で治療していたが,入院45日目に血栓性血小板減少性紫斑病を発症,その6日後より血漿交換療法を計9回施行し,改善を認めた.後日von Willebrand factor切断酵素活性は12%と低下していたことが判明した.血栓性血小板減少性紫斑病の発症には,von Willebrand factor切断酵素活性の低下やそのImmunogloblin G型インヒビターの存在が関与しているといわれている.本症例でもvon Willebrand factor切断酵素活性の低下が認められた.また,強皮症に合併した血栓性血小板減少性紫斑病と強皮症腎クリーゼは病態が似ているが,治療法が異なり鑑別が重要である.両病態を比較しながら本症例について報告する(著者抄録)","subitem_description_type":"Abstract"}]},"item_10002_publisher_8":{"attribute_name":"出版者","attribute_value_mlt":[{"subitem_publisher":"静岡赤十字病院"}]},"item_10002_source_id_11":{"attribute_name":"書誌レコードID","attribute_value_mlt":[{}]},"item_10002_source_id_9":{"attribute_name":"ISSN","attribute_value_mlt":[{"subitem_source_identifier":"0911-9833","subitem_source_identifier_type":"ISSN"}]},"item_10002_version_type_20":{"attribute_name":"著者版フラグ","attribute_value_mlt":[{"subitem_version_resource":"http://purl.org/coar/version/c_970fb48d4fbd8a85","subitem_version_type":"VoR"}]},"item_creator":{"attribute_name":"著者","attribute_type":"creator","attribute_value_mlt":[{"creatorNames":[{"creatorName":"大久保, 彩子"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"山崎, 哲"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"曽我, 隆義"}],"nameIdentifiers":[{},{}]}]},"item_files":{"attribute_name":"ファイル情報","attribute_type":"file","attribute_value_mlt":[{"accessrole":"open_date","date":[{"dateType":"Available","dateValue":"2022-12-20"}],"displaytype":"simple","filename":"jrcsh2501_85-90.pdf","filesize":[{"value":"3.1 MB"}],"format":"application/pdf","licensetype":"license_note","mimetype":"application/pdf","url":{"label":"pdf008985","url":"https://redcross.repo.nii.ac.jp/record/18439/files/jrcsh2501_85-90.pdf"},"version_id":"48cab0ff-687b-4c7b-ba10-fcf65c518bbf"}]},"item_keyword":{"attribute_name":"キーワード","attribute_value_mlt":[{"subitem_subject":"von Willebrand因子","subitem_subject_scheme":"Other"},{"subitem_subject":"強皮症","subitem_subject_scheme":"Other"},{"subitem_subject":"血漿交換","subitem_subject_scheme":"Other"},{"subitem_subject":"紫斑病","subitem_subject_scheme":"Other"},{"subitem_subject":"血栓性血小板減少性","subitem_subject_scheme":"Other"},{"subitem_subject":"systemic sclerosis","subitem_subject_language":"en","subitem_subject_scheme":"Other"},{"subitem_subject":"thrombotic thrombocytopenic purpura","subitem_subject_language":"en","subitem_subject_scheme":"Other"},{"subitem_subject":"von Willebrand factor-cleaving protease","subitem_subject_language":"en","subitem_subject_scheme":"Other"}]},"item_language":{"attribute_name":"言語","attribute_value_mlt":[{"subitem_language":"jpn"}]},"item_resource_type":{"attribute_name":"資源タイプ","attribute_value_mlt":[{"resourcetype":"departmental bulletin paper","resourceuri":"http://purl.org/coar/resource_type/c_6501"}]},"item_title":"強皮症に血栓性血小板減少性紫斑病を合併した1例","item_titles":{"attribute_name":"タイトル","attribute_value_mlt":[{"subitem_title":"強皮症に血栓性血小板減少性紫斑病を合併した1例"},{"subitem_title":"Thrombotic Thrombocytopenic Purpura in The Setting of Systemic Sclerosis","subitem_title_language":"en"}]},"item_type_id":"10002","owner":"29","path":["407"],"pubdate":{"attribute_name":"公開日","attribute_value":"2022-12-20"},"publish_date":"2022-12-20","publish_status":"0","recid":"18439","relation_version_is_last":true,"title":["強皮症に血栓性血小板減少性紫斑病を合併した1例"],"weko_creator_id":"29","weko_shared_id":-1},"updated":"2023-06-20T17:39:57.305862+00:00"}