{"created":"2023-06-20T15:59:42.555696+00:00","id":17719,"links":{},"metadata":{"_buckets":{"deposit":"cec3b655-8750-4b20-a02c-2295b847601e"},"_deposit":{"created_by":28,"id":"17719","owners":[28],"pid":{"revision_id":0,"type":"depid","value":"17719"},"status":"published"},"_oai":{"id":"oai:redcross.repo.nii.ac.jp:00017719","sets":["172:173:642"]},"author_link":["67256","67250","67257","67252","67253","67255","67251","67254"],"item_10001_biblio_info_7":{"attribute_name":"書誌情報","attribute_value_mlt":[{"bibliographicIssueDates":{"bibliographicIssueDate":"2021-03-31","bibliographicIssueDateType":"Issued"},"bibliographicPageEnd":"12","bibliographicPageStart":"9","bibliographicVolumeNumber":"38","bibliographic_titles":[{"bibliographic_title":"日本赤十字社和歌山医療センター医学雑誌"},{"bibliographic_title":"Medical Journal of Japanese Red Cross Wakayama Medical Center","bibliographic_titleLang":"en"}]}]},"item_10001_description_5":{"attribute_name":"抄録","attribute_value_mlt":[{"subitem_description":"筋疾患は、皮膚筋炎をはじめとする「炎症性筋疾患」、骨格筋の壊死・再生を主とする遺伝性筋疾患である「筋ジストロフィー」、そしてミトコンドリア病等のその他のミオパチーに大別される。一般的に炎症性筋疾患では、ステロイドをはじめとする免疫治療が奏功するが、なかには治療抵抗性の疾患もある。 一方、筋ジストロフィーは、現時点では原因治療ができないものが多いが、2020年には、デュシェンヌ型筋ジストロフィーに対して日本で初めて実用化されるエクソン・スキップ治療薬が製造販売の承認をうけるなど、疾患によっては原因治療が可能になりつつある。\n　診断については、例えばトリプレット病の一つである筋強直性ジストロフィーは、特徴的な臨床症状から疑うことが容易であり、筋生検を施行せずに遺伝子診断で診断が確定する。一方、多くの筋疾患は確信をもって臨床診断ができるほどの特徴やマーカーをもっていないため、的確な診断と適切な治療のためには筋生検が必要となる。 \n　本稿の目的は、当院での筋生検症例をレビューし、今後の筋疾患診療の参考となる有用な情報を提供することである。\n","subitem_description_type":"Abstract"}]},"item_10001_full_name_3":{"attribute_name":"著者別名","attribute_value_mlt":[{"nameIdentifiers":[{}],"names":[{"name":"YAMASHITA, Hirofumi"}]},{"nameIdentifiers":[{}],"names":[{"name":"KAMBE, Daisuke"}]},{"nameIdentifiers":[{}],"names":[{"name":"NARUMIYA, Yuji"}]},{"nameIdentifiers":[{}],"names":[{"name":"MIURA, Satoshi"}]}]},"item_10001_heading_23":{"attribute_name":"見出し","attribute_value_mlt":[{"subitem_heading_banner_headline":"総説","subitem_heading_language":"ja"}]},"item_10001_publisher_8":{"attribute_name":"出版者","attribute_value_mlt":[{"subitem_publisher":"日本赤十字社和歌山医療センター"}]},"item_10001_relation_16":{"attribute_name":"情報源","attribute_value_mlt":[{"subitem_relation_name":[{"subitem_relation_name_text":"日本赤十字社和歌山医療センター"}]}]},"item_10001_rights_15":{"attribute_name":"権利","attribute_value_mlt":[{"subitem_rights":"日本赤十字社和歌山医療センター"}]},"item_10001_source_id_11":{"attribute_name":"書誌レコードID","attribute_value_mlt":[{"subitem_source_identifier":"AN1051395X","subitem_source_identifier_type":"NCID"}]},"item_10001_source_id_9":{"attribute_name":"ISSN","attribute_value_mlt":[{"subitem_source_identifier":"1341-9927","subitem_source_identifier_type":"ISSN"}]},"item_10001_version_type_20":{"attribute_name":"著者版フラグ","attribute_value_mlt":[{"subitem_version_resource":"http://purl.org/coar/version/c_970fb48d4fbd8a85","subitem_version_type":"VoR"}]},"item_creator":{"attribute_name":"著者","attribute_type":"creator","attribute_value_mlt":[{"creatorNames":[{"creatorName":"山下, 博史"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"神辺, 大輔"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"成宮, 悠爾"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"三浦, 聖史"}],"nameIdentifiers":[{}]}]},"item_files":{"attribute_name":"ファイル情報","attribute_type":"file","attribute_value_mlt":[{"accessrole":"open_date","date":[{"dateType":"Available","dateValue":"2021-05-24"}],"displaytype":"detail","filename":"02山下.pdf","filesize":[{"value":"910.1 kB"}],"format":"application/pdf","licensetype":"license_note","mimetype":"application/pdf","url":{"label":"Wakayama38_02","url":"https://redcross.repo.nii.ac.jp/record/17719/files/02山下.pdf"},"version_id":"5f8f1125-754b-4f5b-9e06-825cb01d897c"}]},"item_keyword":{"attribute_name":"キーワード","attribute_value_mlt":[{"subitem_subject":"炎症性筋疾患","subitem_subject_scheme":"Other"},{"subitem_subject":"筋炎","subitem_subject_scheme":"Other"},{"subitem_subject":"筋ジストロフィー","subitem_subject_scheme":"Other"},{"subitem_subject":"ミオパチー","subitem_subject_scheme":"Other"},{"subitem_subject":"筋生検","subitem_subject_scheme":"Other"},{"subitem_subject":"inflammatory myositis","subitem_subject_language":"en","subitem_subject_scheme":"Other"},{"subitem_subject":"muscular dystrophy","subitem_subject_language":"en","subitem_subject_scheme":"Other"},{"subitem_subject":"myopathy","subitem_subject_language":"en","subitem_subject_scheme":"Other"},{"subitem_subject":"muscle biopsy","subitem_subject_language":"en","subitem_subject_scheme":"Other"}]},"item_language":{"attribute_name":"言語","attribute_value_mlt":[{"subitem_language":"jpn"}]},"item_resource_type":{"attribute_name":"資源タイプ","attribute_value_mlt":[{"resourcetype":"journal article","resourceuri":"http://purl.org/coar/resource_type/c_6501"}]},"item_title":"当院にて施行した筋生検症例のレビュー","item_titles":{"attribute_name":"タイトル","attribute_value_mlt":[{"subitem_title":"当院にて施行した筋生検症例のレビュー"}]},"item_type_id":"10001","owner":"28","path":["642"],"pubdate":{"attribute_name":"公開日","attribute_value":"2021-05-24"},"publish_date":"2021-05-24","publish_status":"0","recid":"17719","relation_version_is_last":true,"title":["当院にて施行した筋生検症例のレビュー"],"weko_creator_id":"28","weko_shared_id":-1},"updated":"2023-06-20T17:54:59.787835+00:00"}