{"created":"2023-06-20T15:59:36.896722+00:00","id":17579,"links":{},"metadata":{"_buckets":{"deposit":"c7d8be6f-3832-4b78-a744-19ffd169e52a"},"_deposit":{"created_by":53,"id":"17579","owners":[53],"pid":{"revision_id":0,"type":"depid","value":"17579"},"status":"published"},"_oai":{"id":"oai:redcross.repo.nii.ac.jp:00017579","sets":["615:616:644"]},"author_link":["66854","66848","66850","66853","66851","66852","66847","66849"],"item_10001_biblio_info_7":{"attribute_name":"書誌情報","attribute_value_mlt":[{"bibliographicIssueDates":{"bibliographicIssueDate":"2020-11-30","bibliographicIssueDateType":"Issued"},"bibliographicPageEnd":"38","bibliographicPageStart":"35","bibliographicVolumeNumber":"31","bibliographic_titles":[{"bibliographic_title":"岡山赤十字病院医学雑誌"},{"bibliographic_title":"The Okayama Red Cross Hospital Journal of Medicine","bibliographic_titleLang":"en"}]}]},"item_10001_description_5":{"attribute_name":"抄録","attribute_value_mlt":[{"subitem_description":"症例は98歳，女性．既往歴に左腎盂尿管移行部狭窄症があり，全身麻酔下での尿管ステン\nトの定期交換中であった．排尿障害に対しては4 年前からジスチグミン臭化物の内服中であ\nり，副作用なく経過していた．尿管ステント交換術目的に入院され，手術予定の12時間前か\nら絶食， 5 時間前の絶飲食の上，ジスチグミン臭化物の内服を行った．内服4 時間後から，\n嘔気，腹痛，下痢，唾液分泌過多を認め，血液検査でコリンエステラーゼ30U/I と低下がみ\nられ，コリン作動性クリーゼと診断した．直ちに硫酸アトロピン投与とジスチグミン臭化物\nの内服を中止し，症状も改善した．ジスチグミン臭化物の添付文書には，イヌの動物実験で\n絶食によりCmax が約9.4倍，AUC 0 -24が約6.6倍高値を示したとの記載がある．今回我々は\n絶食時のジスチグミン臭化物投与により血中濃度が上昇し，コリン作動性クリーゼを発症し\nたと考えられた1 例を経験したので，若干の文献的考察を加えて報告する．","subitem_description_type":"Abstract"}]},"item_10001_publisher_8":{"attribute_name":"出版者","attribute_value_mlt":[{"subitem_publisher":"岡山赤十字病院"}]},"item_10001_source_id_9":{"attribute_name":"ISSN","attribute_value_mlt":[{"subitem_source_identifier":"0915-8073","subitem_source_identifier_type":"ISSN"}]},"item_creator":{"attribute_name":"著者","attribute_type":"creator","attribute_value_mlt":[{"creatorNames":[{"creatorName":"小田, 浩司"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"笹岡, 丈人"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"榮枝, 一磨"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"山下, 真弘"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"花房, 伸幸"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"甲斐, 誠二"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"森, 英樹"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"竹中, 皇"}],"nameIdentifiers":[{}]}]},"item_files":{"attribute_name":"ファイル情報","attribute_type":"file","attribute_value_mlt":[{"accessrole":"open_date","date":[{"dateType":"Available","dateValue":"2020-12-10"}],"displaytype":"simple","filename":"04-1　症例　小田 p.35-38.pdf","filesize":[{"value":"2.3 MB"}],"format":"application/pdf","licensetype":"license_11","mimetype":"application/pdf","url":{"label":"oayam000031","url":"https://redcross.repo.nii.ac.jp/record/17579/files/04-1　症例　小田 p.35-38.pdf"},"version_id":"d9c94930-740e-4517-a3fc-2a494d46b4ad"}]},"item_keyword":{"attribute_name":"キーワード","attribute_value_mlt":[{"subitem_subject":"distigmine bromide","subitem_subject_language":"en","subitem_subject_scheme":"Other"},{"subitem_subject":"cholinergic crisis","subitem_subject_language":"en","subitem_subject_scheme":"Other"}]},"item_language":{"attribute_name":"言語","attribute_value_mlt":[{"subitem_language":"jpn"}]},"item_resource_type":{"attribute_name":"資源タイプ","attribute_value_mlt":[{"resourcetype":"journal article","resourceuri":"http://purl.org/coar/resource_type/c_6501"}]},"item_title":"絶食時のジスチグミン臭化物内服を契機にコリン作動性クリーゼを発症した1 例","item_titles":{"attribute_name":"タイトル","attribute_value_mlt":[{"subitem_title":"絶食時のジスチグミン臭化物内服を契機にコリン作動性クリーゼを発症した1 例"},{"subitem_title":"A case of cholinergic crisis caused by oral administration of distigmine bromide during fasting","subitem_title_language":"en"}]},"item_type_id":"10001","owner":"53","path":["644"],"pubdate":{"attribute_name":"公開日","attribute_value":"2021-02-01"},"publish_date":"2021-02-01","publish_status":"0","recid":"17579","relation_version_is_last":true,"title":["絶食時のジスチグミン臭化物内服を契機にコリン作動性クリーゼを発症した1 例"],"weko_creator_id":"53","weko_shared_id":-1},"updated":"2023-06-20T17:57:58.561103+00:00"}