@article{oai:redcross.repo.nii.ac.jp:00016479, author = {Koichi, Yamashita and Hirofumi, Yamasaki and Shinya, Hara and Seiji, Hirota and Yuichi, Shimazu and Kumiko, Nishimori and Tsubasa, Murakami and Nana, Kameda and Yayoi, Shibata and Eri, Fujimoto and Kentarou, Yamamoto and Yutaro, Yamamoto and Toshiyuki, Nunomura and Takashi, Hashizume and Takaaki, Yamashita}, issue = {1}, journal = {高知赤十字病院医学雑誌, Medical Journal of Japanese Red Cross Kochi Hospital}, month = {Mar}, note = {We reported a case of a 51-year-old woman with acute respiratory failure for whom ventricular septum defect combined with right-left shunt was successfully performed with the use of high-flow nasal cannula oxygenation (HFNCO) therapy. She had suffered from ventricular septum defect (VSD) and pulmonary artery banding was performed at four-year old. However, residual VSD had not been pointed out. Until today, she had been able to work and do housework. When she suffered from pneumonia and admitted to the hospital, she also pointed out chronic cardiac failure combined with pulmonary hypertension (pulmonary arterial pressure 115/45(76) mmHg, pulmonary vascular resistance 874 dyne/sec/cm5). Thereafter, home oxygen therapy (HOT) was started (2 L/min O2). This time, she suffered from pneumonia and hypoxemia under HOT (SpO2 84 %). She complained of dyspnea even at rest and had labored breathing through pursed lips after a short conversation, defined as class IV in the Hugh-Jones classification. She was transferred to our intensive care unit (ICU) and underwent HFNCO (Flow rate 60 L/min, FiO2 0.6). After starting HFNCO, respiratory rate was decreased from 35 to 25 times/min and dyspnea was improved immediately. Day 5, she transferred to regular ward. Day 7, HFNCO was stopped and conventional oxygen therapy was started. The patient was transferred back to the local hospital for rehabilitation on Day 15.}, pages = {65--68}, title = {A case report of High-Flow Nasal Cannula Oxygenation therapy for acute respiratory failure in patients with ventricular septum defect combined with right-left shunt(和訳中)}, volume = {24}, year = {2020} }