@article{oai:redcross.repo.nii.ac.jp:00014116, author = {Naoto, Kuroda and Saki, Akazawa and Takushi, Naroda and Masato, Tamura and Kenji, Yorita and Yosuke, Fukiishi and Hideo, Fukuhara and Takashi, Karashima and Keiji, Inoue}, issue = {1}, journal = {高知赤十字病院医学雑誌, Medical Journal of Kochi Red Cross Hospital}, month = {Mar}, note = {The prognosis of chromophobe renal cell carcinoma (RCC) is generally favorable. However, some investigations argue against this point of view. In this article, we performed clinicopathologic study of eight cases of chromophobe RCC with focus on prognostic factors. The incidence of chromophobe RCC accounts for 7.3% of total renal tumors. In six patients, tumor was incidentally discovered. Aggressive form was observed in three patients who died of disease in one or showed the distant metastasis in two. Four tumors macroscopically showed more than 8 cm in maximum diameter, which all showed necrosis. Among these tumors, three tumors showed pathologically more than stage III, more than CTG 2, and vascular invasion. Two among these three tumors contained unusual morphological finding, namely neuroendocrine differentiation or breast cancer-like morphology. Five tumors showed CTG 1 and Stage I, which showed neither recurrence nor metastasis. Finally, several factors such as more than 8cm in maximum diameter, macroscopic necrosis, vascular invasion, more than CTG 2 and usual histologic features including neuroendocrine differentiation and mammary-like carcinoma may be worse prognostic indicators in chromophobe RCC.}, pages = {7--12}, title = {Clinicopathology study of eight cases of chromophobe renal cell carcinoma(和訳中)}, volume = {23}, year = {2019} }