{"created":"2023-06-20T15:56:53.890120+00:00","id":13950,"links":{},"metadata":{"_buckets":{"deposit":"631fa607-026a-4fab-8387-c56bf16c0fd6"},"_deposit":{"created_by":22,"id":"13950","owners":[22],"pid":{"revision_id":0,"type":"depid","value":"13950"},"status":"published"},"_oai":{"id":"oai:redcross.repo.nii.ac.jp:00013950","sets":["100:90:545"]},"author_link":["50648","50650","50649","50647","50646"],"item_5_biblio_info_7":{"attribute_name":"書誌情報","attribute_value_mlt":[{"bibliographicIssueDates":{"bibliographicIssueDate":"2018-12","bibliographicIssueDateType":"Issued"},"bibliographicPageEnd":"25","bibliographicPageStart":"21","bibliographicVolumeNumber":"39","bibliographic_titles":[{"bibliographic_title":"京都第二赤十字病院医学雑誌"},{"bibliographic_title":"Medical journal of Kyoto Second Red Cross Hospital","bibliographic_titleLang":"en"}]}]},"item_5_description_5":{"attribute_name":"抄録","attribute_value_mlt":[{"subitem_description":"当院に通院中の難治性好酸球性喘息の8 例に対してメポリズマブを投与した．使用前後の末梢血好酸球数，血漿IgE，呼気一酸化窒素（fraction of exhaled nitric oxide : FeNO），1 秒量を測定し，さらに喘息コントロールテスト（asthma control test : ACT）を用いてコントロール状況を評価した．末梢血好酸球数は全例で大きく低下した．血漿IgE は投与前後で変化しなかった．FeNO は若干低下する傾向が見られたが，1 秒量は増加しなかった．また，ACT 値は6 例で上昇した．ACT 値の上昇した6 例でメポリズマブは有効と考えられたが，低下した2 例も存在した．メポリズマブの適正な使用のためには何らかの指標が求められ，そのためには症例の蓄積が必要である．","subitem_description_type":"Abstract"}]},"item_5_full_name_3":{"attribute_name":"著者別名","attribute_value_mlt":[{"nameIdentifiers":[{"nameIdentifierScheme":"WEKO"},{"nameIdentifierScheme":"CiNii ID","nameIdentifierURI":"http://ci.nii.ac.jp/nrid/9000398395613 "}],"names":[{"name":"FURUTANI , Wataru"}]}]},"item_5_publisher_8":{"attribute_name":"出版者","attribute_value_mlt":[{"subitem_publisher":"京都第二赤十字病院"}]},"item_5_source_id_11":{"attribute_name":"書誌レコードID","attribute_value_mlt":[{"subitem_source_identifier":"AN00357778 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豊"}],"nameIdentifiers":[{},{}]}]},"item_files":{"attribute_name":"ファイル情報","attribute_type":"file","attribute_value_mlt":[{"accessrole":"open_date","date":[{"dateType":"Available","dateValue":"2019-01-24"}],"displaytype":"simple","filename":"MJKSRCH39_21.pdf","filesize":[{"value":"369.3 kB"}],"format":"application/pdf","licensetype":"license_note","mimetype":"application/pdf","url":{"label":"kyo2_000106","url":"https://redcross.repo.nii.ac.jp/record/13950/files/MJKSRCH39_21.pdf"},"version_id":"6485782a-675d-4995-a329-7d46f15e4d9f"}]},"item_keyword":{"attribute_name":"キーワード","attribute_value_mlt":[{"subitem_subject":"好酸球性喘息","subitem_subject_scheme":"Other"},{"subitem_subject":"好酸球","subitem_subject_scheme":"Other"},{"subitem_subject":"メポリズマブ","subitem_subject_scheme":"Other"},{"subitem_subject":"Mepolizumab","subitem_subject_scheme":"Other"},{"subitem_subject":"喘息コントロールテスト","subitem_subject_scheme":"Other"},{"subitem_subject":"asthma control test","subitem_subject_scheme":"Other"},{"subitem_subject":"一酸化窒素","subitem_subject_scheme":"Other"},{"subitem_subject":"Eosinophilic asthma","subitem_subject_language":"en","subitem_subject_scheme":"Other"},{"subitem_subject":"Mepolizumab","subitem_subject_language":"en","subitem_subject_scheme":"Other"},{"subitem_subject":"Fractional exhaled nitric oxide (FeNO)","subitem_subject_language":"en","subitem_subject_scheme":"Other"},{"subitem_subject":"Forced expiratory volume in one second (FEV1)","subitem_subject_language":"en","subitem_subject_scheme":"Other"},{"subitem_subject":"Asthma Control Test (ACT)","subitem_subject_language":"en","subitem_subject_scheme":"Other"}]},"item_language":{"attribute_name":"言語","attribute_value_mlt":[{"subitem_language":"jpn"}]},"item_resource_type":{"attribute_name":"資源タイプ","attribute_value_mlt":[{"resourcetype":"technical report"}]},"item_title":"難治性好酸球喘息に対する メポリズマブ（Mepolizumab）の効果","item_titles":{"attribute_name":"タイトル","attribute_value_mlt":[{"subitem_title":"難治性好酸球喘息に対する メポリズマブ（Mepolizumab）の効果"},{"subitem_title":"Eight cases of intractable eosinophilic asthma treated with mepolizumab","subitem_title_language":"en"}]},"item_type_id":"5","owner":"22","path":["545"],"pubdate":{"attribute_name":"公開日","attribute_value":"2019-01-24"},"publish_date":"2019-01-24","publish_status":"0","recid":"13950","relation_version_is_last":true,"title":["難治性好酸球喘息に対する メポリズマブ（Mepolizumab）の効果"],"weko_creator_id":"22","weko_shared_id":-1},"updated":"2023-06-20T18:50:22.727447+00:00"}